NL-OMON20133已完成不适用
INTENDED
/A0 个研究点目标入组 44 人开始时间: 待定最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 44
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •Healthy controls:
- •-22 healthy controls 40-70 years, BMI <30kg/m2
- •- 11 controls of Caucasian descent and 11 of Surinamese descent
- •Type 2 Diabetes (T2D) subjects:
- •-22 T2D patients (11 of Caucasian descent and 11 of Surinamese descent)
- •-40-70 years
- •-BMI 25-35
- •-Stable anti diabetic drugs for 3 months (metformin is obligatory)
- •-All on statin
- •-Stable medication uses past 3 months
- •-Able to give informed consent
排除标准
- •-Previous major cardiovascular event (e.g. AMI/stroke/TIA)
- •-GLP1 nor insulin
- •-antibiotic use in the past 3 months
- •-Probiotic or symbiotic usage
- •-Pregnant women,
- •-Chronic illness (including a known history of heart failure, renal failure (eGFR <30 ml/min), pulmonary disease, gastrointestinal disorders, or hematologic diseases), or other inflammatory diseases
- •-Active infection,
- •-Previous intestinal (e.g., bowel resection/reconstruction) surgery
- •-Smoking (can also influence microbiota)
- •-Vegetarian diet (since they have different microbiota)
- •->6 alcohol units per day or >14 alcohol units per week
- •-Active malignancy
- •-HbA1c >9% (75mmol/mol)
- •-The subject is already involved in a clinical trial
研究者
相似试验
进行中（未招募）
1 期
Eurotrophins MImetic compound for modulation of ischemia/reperfusion damage in Liver transplantation with Extended criteria Donors, a phase I/II explorative, open label, controlled, randomized studyCTIS2023-508977-10-00Mimetech S.r.l.24
尚未招募
不适用
Impact of diet plus exercise on endothelial function, arterial stiffness and blood pressure in stage 1 hypertensive patients: results from the ?INTreat randomized, open-label trialHypertension.Essential (primary) hypertensionIRCT20200307046715N1Mitropoleos 92 St91
进行中（未招募）
1 期
Evaluation de la pharmacodynamie, de l’efficacité et de la tolérance de 2 doses de Simulect® (40 ou 80 mg) en association ou non à un inhibiteur de la calcineurine.Renal transplantationEUCTR2010-024231-16-FRovartis Pharma S.A.S50
进行中（未招募）
1 期
/AMedDRA version: 14.1Level: PTClassification code 10018209Term: Gestational diabetesSystem Organ Class: 10027433 - Metabolism and nutrition disordersEUCTR2011-004221-28-FRASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
进行中（未招募）
1 期
on applicableEUCTR2020-001287-28-FRAssitance Publique-Hôpitaux de Paris60