The effect of nutrition on growth, body composition and bone mineralization of late preterm infants.
- Conditions
- <p>English: late preterms, nutrition, growth, body composition. Dutch: laat-prematuren, voeding, groei, lichaamssamenstelling</p>
- Registration Number
- NL-OMON28261
- Lead Sponsor
- VU University Medical Center, Amsterdam
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 300
Inclusion Criteria
birth between 32 0/7 and 35 6/7 weeks gestation
- inclusion will only take place when written informed consent from both parents is obtained
Exclusion Criteria
- gastro-intestinal surgery and disease known to influence growth (i.e. cystic fibrosis and severe gastro-oesophageal reflux);
- known presence of growth hormone, IGF-1 or other pituitary hormone deficiencies;
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>- Growth (weight, length, head circumference);<br>- Body composition (fat mass, lean mass)</p>
- Secondary Outcome Measures
Name Time Method <p>- Cardiometabolic risk factors (insulin, glucose, triglycerides, cholesterol, blood pressure);<br>- bone mineralization (bone mineral density);<br>- endocrine parameters (IGF-I, IGF-II, IGF-BP3, FGF-23)</p>