Effect of Intra Dialytic Aerobic Exercises Versus Active Free Exercises on Cognitive Function and Functional Capacity in Hemodialytic Patients
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 69
- 主要终点
- 6-Minutes walk test
研究概览
简要总结
o Sixty-nine adult patients from both sexes. They were suffering from ESRD on maintenance hemodialysis, their age ranged from50-60 years old were selected from hemodialysis unit at Itay El Baroud central hospital. They were referred by the physician.
详细描述
Ⅰ-Subjects:
o Sixty-nine adult patients from both sexes. They were suffering from ESRD on maintenance hemodialysis, their age ranged from50-60 years old were selected from hemodialysis unit at Itay El Baroud central hospital. They were referred by the physician.
Study group (A): the study group consisted of (23) patients who received aerobic exercise in form of (foot pedal exerciser) for 20 Minutes for each session, 3 sessions per week, for 8 weeks plus maintain on their medical treatment and hemodialysis.
Study group (B): the study group consisted of (23) who received active free range of motion exercise (open kinetic chain active free range of motion) for 20 minutes for each session, 3 sessions per week, for 8 weeks plus maintain on their medical treatment and hemodialysis.
Control group (C): the control group consisted of (23) patients who were maintained on their medical treatment and hemodialysis.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 50 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All patients were included according to the following criteria:
- •Age between 50-60years.
- •The patients had been on hemodialysis for at least 3 months with three sessions per week for 3-4hr per session.
- •The patients were diagnosed with end stage renal failure (stage5 CKD) on maintenance regular HD (three sessions/week (on alternate days), for four hours/session) for more than three months. (Receiving HD through uncomplicated arm arteriovenous (A-V) fistula
- •Under medical control
- •Both men and women were enrolled
- •Body math index ranged from 18,5- 24.9 kg/m²
排除标准
- •Patients who experienced or had one or more of the following were excluded from the study:
- •Patients with resting systolic blood pressure >200 mmHg and/or diastolic blood pressure >120 mmHg.
- •patients with neurological problems (e.g. stroke, head injury)
- •patients with musculoskeletal problems (e.g. sever osteoarthritis or difficulties in ambulation)
- •Patients with uncontrolled pulmonary disease. (e.g. exaggerated chronic obstructive pulmonary disease, acute asthma)
- •Patients with mental health problems and cognitive impairment due to inability to teach them how to make respiratory training.
- •Any patient who missed more than two weeks of the program or want to terminate the program.
- •Severe obesity (BMI >35)
- •Presence of malignant disease.
- •Patients with unstable angina, uncontrolled cardiac arrhythmia, decompensated heart failure, acute pericarditis or myocarditis.
- •The patients had hearing impairment or mental disorders.
结局指标
主要结局
6-Minutes walk test
时间窗: 8 weeks
The 6-min walk test (6MWT) is frequently used to measure physical function in transplanted patients
Fatigue Questionnaire (Fatigue Severity Scale)
时间窗: 8 weeks
The Fatigue Severity Scale it used to assess the level of fatigue. The Fatigue Severity Scale scores range from 9 to 36 where higher scores indicate worse fatigue and lower scores indicate improvement in fatigue.
次要结局
- The Mini-Cog test(8 weeks)
- Laboratory investigation (Urea analysis)(8 weeks)
- Laboratory investigation (creatinine analysis)(8 weeks)
研究者
Faten Mahmoud
Consultant of Physical Therapy, Chest Hospital, Damanhour, Elbeheira
Cairo University