Secondary caries in situ: minimal gap size and MMP inhibitor

Completed

• Conditions: caries; caries adjacent to restorations; recurrent caries

• Registration Number: NL-OMON44491
• Lead Sponsor: Radboud Universitair Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 16

Inclusion Criteria

- subjects able to wear a removable appliance for 3 weeks, 24 hrs per day
- adults (>=18 years) with healthy dentition

Exclusion Criteria

- active caries
- periodontitis DPSI > 2
- ASA > 2
- removable prosthetic appliance

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Lesion depth (µm) and mineral loss (µm.vol%) of (secondary) caries wall lesions</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>N.A.</p><br>