RBR-10fghxtm
Withdrawn
未知
Controlled and randomised clinical study on the effects of exercise associated with antioxidant supplementation on redox and immuno-metabolic regulation in patients with diabetes renal disease
Pontifícia Universidade Católica do Paraná0 sitesNovember 30, 2021
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Pontifícia Universidade Católica do Paraná
- Status
- Withdrawn
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Female and male; ages 40 to 65; staging of chronic kidney disease 3 and 4 degree; body mass index: lower than obesity grade 2; glomerular filtration rate estimated by the equation developed by Chronic Renal Disease Epidemiology Collaboration (CKDEPI) and according to stage 3 and 4; presence of optimized drug therapy and without the prediction of change in drug doses of renin\-angiotensin aldosterone system blockers, mineralocorticoid antagonist or sodium cotransporter inhibitors and glucose with stable doses up to 4 weeks prior to randomization and during the 7 months of intervention.
Exclusion Criteria
- •Heart failure; severe coronary heart disease indicating physical activity or cardiovascular surgery (e.g. coronary bypass, valvar exchange or angioplasty) within the last 6 months; uncontrolled cardiovascular disease; percentage of glycated haemoglobin greater than 9; chronic lung disease; active viral infections; neurological and mental disorders, musculoskeletal impairment that prevents physical exercise, malignancy (except epidermoid carcinoma) or debilitating and warfarin users.
Outcomes
Primary Outcomes
Not specified
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