Clinical Evaluation of the Efficacy of Mixed Vegetables and Fruits Juice on Perennial Allergic Rhinitis of Healthy Subjects
- Conditions
- Healthy adults
- Registration Number
- JPRN-UMIN000037921
- Lead Sponsor
- Kagome CO., LTD.
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 96
Not provided
1) Subjects who have positive results on serum allergen-specific IgE against Poaceae or Ambrosia artemisiifolia and are judged that symptoms of allergic rhinitis depend on their antigen. 2) Subjects who have non-allergic rhinitis 3) Subjects who have acute rhinitis, sinusitis, nasal polyp, hypertrophic rhinitis, and deviated septum. 4) Subjects who take medicines such as anti-histamine and anti-allergy. 5) Subjects who have bronchial asthma as a complication. 6) Subjects who currently receive or have previously received allergen immunotherapy. 7) Subjects who have current medical history of serious disease in heart, liver, kidney and digestive system. 8) Subjects who have previous medical history of serious disease and be judged unsuitable for this study by principal investigator. 9) Subjects who will be treated or take medicine for perennial allergic rhinitis during this study period. 10) Subjects who have vegetables-based diet 11) Subjects who intake the medicines, the foods for specified health uses and/or the health foods that are concerned their influence to test results. 12) Pregnant or expected pregnant, planning pregnant during this study period and lactating women 13) Subjects who cannot take test food and record diary as instructions. 14) Subjects who habitually consume higher amount of alcohol (=> 60 g alcohol/day) 15) Subjects with risk of allergy regarding to this study 16) Subjects who are participating in the other clinical tests. Subjects who participated in the other clinical tests within 2-months prior to this study and/or who plan to participate in the other clinical tests. 17) Subjects who donated over defined blood and/or blood components amounts before this study. 18) Subjects who are judged unsuitable for this study by principal investigator and doctors.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method asal symptom score(Record score using a 5-point scale) before and 2, 4, 6, 8 weeks after the intervention with mixed vegetables and fruits juice or placebo.
- Secondary Outcome Measures
Name Time Method asal symptom score (Japan Rhinoconjunctivitis Quality of Life Questionnaire (JRQLQ)), Ocular symptom score, QOL score (JRQLQ), non-specific IgE, Allergen-specific IgE, eosinophil count in nasal discharge, Serum carotenoid concentrations