Renal Artery Calcium and Hypertension

• Conditions: Hypertension; Atherosclerosis

• Registration Number: NCT00388869
• Lead Sponsor: Hadassah Medical Organization

Brief Summary

CT of the abdomen is a very common examination performed for various indications.One of the common findings is vascular calcifications including calcifications of the renal arteries.Calcifications in the carotid arteries and coronary arteries are good predictor for obstructive atherosclerotic disease.Stenosis of the renal arteries can cause symptomatic or asymptomatic hypertension with subsequent clinical sequelae. Therefore early diagnosis of this condition is imperative.

The goal of our study is to investigate the correlation between incidental calcifications of the renal arteries in CT examinations and the presence of actual stenosis of these vessels in patients with and without hypertension.

Detailed Description

Every patient aged 30-100 referred for abdominal CT examination with IV contrast injection will be included in this study (total 300 patients.Prior to the examination relevant clinical data including history of hypertension and predisposing conditions for atherosclerotic disease, will be investigated. The patient will undergo conventional CT with no special procedures. The images will be review by the radiologist for the presence of renal arteries calcifications, renal arteries stenosis,plaque location, plaque burden and characterization and secondary renal pathology.

This study will not change the examination technique and is not associated with any inconvenience to the patients.

Study Timeline

• Status Verified: 2006-10
• Study First Submitted: 2006-10-15
• Study First Submitted QC: 2006-10-16
• Last Update Submitted: 2006-10-16
• Study First Posted: 2006-10-17
• Last Update Posted: 2006-10-17
• Study Start: 2006-11

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 300

Inclusion Criteria

• Every patient referred fo abdominal CT aged 30-100

Exclusion Criteria

• Contraindication for IV contrast injection failure to demonstrate renal arteries with contrast refusal to sign an informed consent

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Trial Locations

Locations (1)

Hadassah Medical Organization; 🇮🇱 Jerusalem, Israel