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临床试验/NCT01191710
NCT01191710Unknown4 期

Is the Clinical Outcome Affected by the Incidence of Progesterone Elevation on the Day of hCG Triggering When Agonist Protocol is Compared to Antagonist Protocol for IVF

Universitair Ziekenhuis Brussel2 个研究点 分布在 1 个国家目标入组 200 人开始时间: 2007年1月最近更新:
适应症

试验速览

阶段
4 期
入组人数
200
试验地点
2
主要终点
Incidence of late progesterone rise on the day of HCG triggering

研究概览

简要总结

The aim is to explore whether the incidence of progesterone rise in the late follicular phase differs between GnRH-agonist and GnRH-antagonist protocols for IVF and whether this has an impact on the probability of pregnancy achievement.

详细描述

In view of the current debate concerning possible differences in efficacy between the two GnRH analogues, the current study aimed to explore whether progesterone control in the late follicular phase differs when GnRH-agonist is used as compared to GnRH-antagonist and if so to what extend does the progesterone rise have an impact on the probability of achieving a pregnancy.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
None

入排标准

年龄范围
21 Years 至 39 Years(Adult)
性别
Female
接受健康志愿者

入选标准

  • age < 39
  • follicle-stimulating hormone (FSH) < 12
  • gonadotropin dose 100-300IU

排除标准

  • endometriosis
  • known endocrine disorder
  • blood analyzed in another laboratory

结局指标

主要结局

Incidence of late progesterone rise on the day of HCG triggering

时间窗: Up to delivery (2010)

次要结局

  • Clinical pregnancy rate Delivery rate(Up to delivery (2010))

研究者

申办方类型
Other

研究点 (2)

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