Is the Clinical Outcome Affected by the Incidence of Progesterone Elevation on the Day of hCG Triggering When Agonist Protocol is Compared to Antagonist Protocol for IVF
试验速览
- 阶段
- 4 期
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- Incidence of late progesterone rise on the day of HCG triggering
研究概览
简要总结
The aim is to explore whether the incidence of progesterone rise in the late follicular phase differs between GnRH-agonist and GnRH-antagonist protocols for IVF and whether this has an impact on the probability of pregnancy achievement.
详细描述
In view of the current debate concerning possible differences in efficacy between the two GnRH analogues, the current study aimed to explore whether progesterone control in the late follicular phase differs when GnRH-agonist is used as compared to GnRH-antagonist and if so to what extend does the progesterone rise have an impact on the probability of achieving a pregnancy.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 21 Years 至 39 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •age < 39
- •follicle-stimulating hormone (FSH) < 12
- •gonadotropin dose 100-300IU
排除标准
- •endometriosis
- •known endocrine disorder
- •blood analyzed in another laboratory
研究组 & 干预措施
Antagonist group
Antagonist protocol for IVF
干预措施: In vitro fertilization (Other)
Agonist group
Long Agonist protocol for IVF
干预措施: In vitro fertilization (Other)
结局指标
主要结局
Incidence of late progesterone rise on the day of HCG triggering
时间窗: Up to delivery (2010)
次要结局
- Clinical pregnancy rate Delivery rate(Up to delivery (2010))