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Homocysteine levels in polycystic ovary syndrome (PCOS) patients

Not Applicable
Completed
Conditions
Improving the metabolic competence in oocytes of PCOS patients undergoing IVF treatment.
Pregnancy and Childbirth
Registration Number
ISRCTN55983518
Lead Sponsor
Acibadem Healthcare
Brief Summary

2023 Results article in https://pubmed.ncbi.nlm.nih.gov/37300649/ (added 12/06/2023)

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Female
Target Recruitment
43
Inclusion Criteria

1. PCOS patients diagnosed using Rotterdam's Criteria
2. Primary infertility for at least 1 year
3. No other condition leading to infertility

Exclusion Criteria

Patients who requested two embryos but implanted only one.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Clinical pregnancy, calculated as number of fetuses with heart activity beyond 20 weeks of gestation per transferred embryo
Secondary Outcome Measures
NameTimeMethod
1. FSH consumption during stimulation, calculated as cumulative number if FSH units injected <br>2. Fertilization rate, calculated as the rate of fertilized oocytes (2 PN) out of the total number of inseminated oocytes <br>3. Blastocyst rate, calculated as the rate of fertilized oocytes reaching the blastocyst stage at 5-6 days <br>4. Biochemical pregnancy, calculated as the rate of positive hCG at 7 days post embryo transfer out of the number of patients receiving an embryo transfer
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