The effect of metformin and insulin in the prevention of preeclampsia
Not Applicable
- Conditions
- Pre-eclampsia.Pre-eclampsia
- Registration Number
- IRCT20220107053652N1
- Lead Sponsor
- Esfahan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 150
Inclusion Criteria
Gestational diabetes
Age of 18-40 years
Single pregnancy
Gestational age between 20-34 weeks
Fasting glucose test more than 95 mg/dl or 2 hours postprandial glucose more than 120 mg
Exclusion Criteria
Having high blood pressure before pregnancy
Previous history of any systemic disease (including cardiovascular, renal, hepatic, and autoimmune diseases)
Addiction and drug abuse
Obesity (Body mass index above 30)
Overt diabetes
Major neonatal malformations
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Blood Pressure. Timepoint: Once every two weeks. Method of measurement: Using a sphygmomanometer.
- Secondary Outcome Measures
Name Time Method Weight. Timepoint: During the period of pregnancy. Method of measurement: Balance.;Fasting blood sugar. Timepoint: The periods during pregnancy. Method of measurement: Using a glucometer.;Blood sugar after eating. Timepoint: The periods during pregnancy. Method of measurement: Using a glucometer.;High proteins in the urine. Timepoint: The periods during pregnancy. Method of measurement: Using urine test.