Retrolaminar Block Versus Erector Spinae Plane Block for Postoperative Analgesia in Laparoscopic Cholecystectomy: A Comparative Randomized Prospective Study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Time to the 1st rescue analgesia
研究概览
简要总结
This prospective, randomized, double-blind clinical trial evaluates the comparative effectiveness of ultrasound-guided retrolaminar block (RLB) and erector spinae plane block (ESPB) for postoperative analgesia in patients undergoing laparoscopic cholecystectomy. A total of 100 ASA I-II patients, aged 20-60 years, will be randomly allocated into two equal groups to receive either RLB or ESPB bilaterally following induction of standardized general anesthesia. The primary outcome is the time to first request for rescue analgesia, while secondary outcomes include total morphine consumption within the first 24 hours, postoperative pain scores assessed using the Numeric Rating Scale (NRS), patient satisfaction, and the incidence of adverse events. Pain assessment will be performed at predefined intervals over the first 24 hours postoperatively. The study aims to determine which technique provides superior analgesia with reduced opioid requirements and improved patient outcomes.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 20 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •• Age from 20 to 60 years.
- •Both sexes.
- •American Society of Anesthesiology (ASA) grade I and II physical status.
- •Patients will undergo cholecystectomy under general anesthesia.
排除标准
- •• Sensitivities or contraindications to the study medications.
- •Infection at the site of injection.
- •Emergency surgery.
- •Body mass index (BMI) >
- •Organic comorbidities.
- •Histories of psychological conditions and/or chronic pain syndromes.
- •Contraindications to regional anesthesia.
- •Severe respiratory, cardiac, hepatic and renal disorders.
- •Pregnancy.
- •Coagulopathy.
- •Opioid addiction.
研究组 & 干预措施
RLB group
干预措施: Retrolaminar Block (RLB) (Biological)
ESPB group
干预措施: Erector spinae plane block (ESPB) (Procedure)
结局指标
主要结局
Time to the 1st rescue analgesia
时间窗: in the 1st 24hr.
次要结局
- Total morphine consumption(in the 1st 24hr.)
- Pain score.(Pain will be assessed at, 2, 4, 6, 8, 12, 18 and 24 hour postoperatively.)
- Degree of patient satisfaction(in the first 24 hours after surgery)
研究者
Esraa Abdallah Mohamed
Resident of Anesthesia, Surgical Intensive Care and Pain Management Faculty of Medicine, Sohag University
Sohag University