Behavioral Treatment of Drug Abuse in SPMI Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 293
- 试验地点
- 8
- 主要终点
- Urinalysis
研究概览
简要总结
The main purpose of this study is to determine if the multifaceted treatment for substance abuse in dual disordered patients is more effective in reducing drug use than a supportive control treatment. The researchers will also determine if adding a case management component (Critical Time Intervention; CTI) to the intervention will increase treatment engagement and retention.
详细描述
Drug and alcohol abuse by people with severe and persistent mental illness (SPMI) is one of the most significant problems facing the public mental health system. We have been conducting a project to develop a multifaceted treatment for substance abuse in dual disordered patients (Behavioral Treatment for Substance Abuse in Schizophrenia; BTSAS). Results have shown that the treatment is well-accepted by patients and has a significant effect on drug use. While BTSAS has been effective at retaining subjects and fostering reduced drug use, a major problem that occurred was low rates of engagement. The main purpose of this study is to determine if BTSAS is more effective in reducing drug use than a supportive control treatment and to determine if adding a case management component (Critical Time Intervention; CTI) will increase treatment engagement and retention in BTSAS.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 55 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •a diagnosis of schizophrenia or schizoaffective disorder or a diagnosis of other severe mental disorder including bipolar disorder, major depression, or severe anxiety disorder (by definition, the patient has worked 25% or less of the past year; and/or the patient receives payment for mental disability)
- •a diagnosis of current dependence for opiates, cocaine, or marijuana
- •ability and willingness to attend treatment sessions for 6 months
- •ability and willingness to provide consent to participate
- •enrolled in mental health care
排除标准
- •documented history of severe neurological disorder or severe head trauma with loss of consciousness
- •severe or profound mental retardation as indicated by chart review
- •inability to effectively participate in the baseline assessments due to intoxication or psychiatric symptoms on two successive appointments
- •had a substantial trial in either intervention of the Evaluation of Behavioral Treatment for Substance Abuse in Schizophrenia protocol (H-20680)
- •inability to attend group sessions due to transportation or other logistical problems
- •inability to attend scheduled treatment sessions on a regular basis for any reason, or to appropriately participate in research activities due to behavioral or psychiatric problems
结局指标
主要结局
Urinalysis
时间窗: Baseline, 2 and 4 months, post and 6-month follow-up, and at each treatment session
次要结局
未报告次要终点
研究者
Melanie Bennett
Associate Professor
University of Maryland, Baltimore