CTRI/2023/03/051129
Not yet recruiting
Phase 2
Comparative Evaluation of Advanced Platelet Rich Fibrin Plus and Enamel Matrix Derivative In The Treatment of Periodontal Intrabony Defects: A Randomized Clinical Trial
Overview
- Phase
- Phase 2
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- OT APPLICABLE
- Status
- Not yet recruiting
- Last Updated
- 3 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Stage II or III Periodontitis.
- •Systemically healthy patient.
- •good level of oral hygiene with Full\-Mouth Bleeding Score \<20% and Full
- •Mouth Plaque Index Score \<20%
- •presence of a minimum one or more 2\-, 3\-, or combined 2â??3\-wall intrabony
- •defect with a defect angle of 20â??40 (±5\) degrees
- •Pocket depths \>\= 6mm measured with UNC 15 probe.
- •Vertical bone loss \>\= 4mm seen on intraoral periapical radiograph.
- •No history of periodontal therapy in the preceding 6months.
- •No use of antibiotics in the preceding 6months which can interfere with bone healing.
Exclusion Criteria
- •With known systemic illness such as Diabetes mellitus, arthritis and osteoporosis.
- •Patients on systemic medications such as corticosteroids or Calcium channel blockers or taking long\-term NSAIDS or taking bisphosphonates
- •or calcium supplements.
- •Use of tobacco in any form and alcohol.
- •Teeth with Grade\-III mobility and/or furcation involvement.
- •Immunocompromised individuals.
- •Pregnant or lactating females.
- •Tooth with hopeless prognosis.
- •Non\-vital tooth with or without periapical pathology.
- •History of radiotherapy therapy in the preceding 1 year in head and neck region.
Outcomes
Primary Outcomes
Not specified
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