跳至主要内容
临床试验/CTRI/2024/10/074899
CTRI/2024/10/074899尚未招募2 期

A Comparative Clinical Study with Udhayabhaskara Ras & Kshara Vasti in the Management of Seropositive & Seronegative Rheumatoid Arthritis W.S.R to Amavata

Dr. Kuncharapu Sandhya Rani1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2024年10月15日最近更新:

试验速览

阶段
2 期
状态
尚未招募
发起方
入组人数
40
试验地点
1
主要终点
To relieve the symptoms of Rheumatoid Arthritis and improve the quality of life

研究概览

简要总结

In present time, due to modern lifestyle, hectic schedule, stress, and many such reasons, incidence of diseases are increasing, one of them is Amavata. The concept of autoimmunity is well explained under the concept of Ama, an intermediate product generated due to the deranged metabolism of the digestive fire triggering the chronic inflammatory process in the body.

Rheumatoid arthritis is a chronic inflammatory disease. In the whole world, rheumatic disease is the most common cause of physical impairment in society. The lives of more than one million people are physically impaired by rheumatic disorders and one fifth of them are severely disabled. The prevalence rate of this disease is about 3%, with male female ratio of 1:3. It occurs throughout the world in all climates and ethnic groups.

Madhavakara was the first person to give a detailed description of Amavata. It effects the individuals, who indulge in viruddhahara (improper and irregular dietary habits) viruddha chesta (improper physical and psychological activities) sedentary habits and people who exercise immediately after intake of unctuous food.

The word "Ama" literally means undigested, toxic or unwholesome product, which is produced in the body due to the weakening of digestive fire. This ama is then carried by vitiated vayu and travel throughout the body and gets accumulated in the joints, which is seat of kapha. As this process continues in all joints, it results in severe pain and swelling in the joints. Here pain is due to vitiated vata and swelling is due to vitiated kapha. When pitta also get aggravated, it causes burning sensation in the joints.

Amavata may be correlated with Rheumatoid arthritis, it is a chronic progressive autoimmune arthropathy characterised by bilateral symmetrical involvement of joints with systemic clinical manifestations. It is basically Sero Positive RA & Sero Negative RA. (In Blood RA factor Positive, and Negative)

研究设计

研究类型
Interventional
分配方式
Na
盲法
None

入排标准

年龄范围
18.00 Year(s) 至 65.00 Year(s)(—)
性别
All

入选标准

  • Patients with clinical features of Amavata.
  • Patients of either gender, aged between
  • Patients who fulfill the revised criteria for Rheumatoid arthritis fixed by the American College of Rheumatology.
  • Patients of both RA factor positive and RA factor negative.
  • Patients who are willing to give consent form.
  • Patients who are eligible for kshara vasti.

排除标准

  • Chronicity of more than 10 years.
  • Pregnant womens and lactating mothers.
  • Having severe crippling deformities.
  • Systemic diseases like uncontrolled Diabetes, Tuberculosis and Hypertension.

结局指标

主要结局

To relieve the symptoms of Rheumatoid Arthritis and improve the quality of life

时间窗: 90 days

次要结局

  • to improve the quality of life by preventing disabilities(90 days)

研究者

发起方
Dr. Kuncharapu Sandhya Rani
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

Dr Kuncharapu Sandhya Rani

Dr. BRKR Govt Ayurvedic Medical college & Hospital

研究点 (1)

Loading locations...

相似试验