Skip to main content
Clinical Trials/CTRI/2024/10/074899
CTRI/2024/10/074899Not yet recruitingPhase 2

A Comparative Clinical Study with Udhayabhaskara Ras & Kshara Vasti in the Management of Seropositive & Seronegative Rheumatoid Arthritis W.S.R to Amavata

Dr. Kuncharapu Sandhya Rani1 site in 1 country40 target enrollmentStarted: October 15, 2024Last updated:

Trial Snapshot

Phase
Phase 2
Status
Not yet recruiting
Sponsor
Enrollment
40
Locations
1
Primary Endpoint
To relieve the symptoms of Rheumatoid Arthritis and improve the quality of life

Study Overview

Brief Summary

In present time, due to modern lifestyle, hectic schedule, stress, and many such reasons, incidence of diseases are increasing, one of them is Amavata. The concept of autoimmunity is well explained under the concept of Ama, an intermediate product generated due to the deranged metabolism of the digestive fire triggering the chronic inflammatory process in the body.

Rheumatoid arthritis is a chronic inflammatory disease. In the whole world, rheumatic disease is the most common cause of physical impairment in society. The lives of more than one million people are physically impaired by rheumatic disorders and one fifth of them are severely disabled. The prevalence rate of this disease is about 3%, with male female ratio of 1:3. It occurs throughout the world in all climates and ethnic groups.

Madhavakara was the first person to give a detailed description of Amavata. It effects the individuals, who indulge in viruddhahara (improper and irregular dietary habits) viruddha chesta (improper physical and psychological activities) sedentary habits and people who exercise immediately after intake of unctuous food.

The word "Ama" literally means undigested, toxic or unwholesome product, which is produced in the body due to the weakening of digestive fire. This ama is then carried by vitiated vayu and travel throughout the body and gets accumulated in the joints, which is seat of kapha. As this process continues in all joints, it results in severe pain and swelling in the joints. Here pain is due to vitiated vata and swelling is due to vitiated kapha. When pitta also get aggravated, it causes burning sensation in the joints.

Amavata may be correlated with Rheumatoid arthritis, it is a chronic progressive autoimmune arthropathy characterised by bilateral symmetrical involvement of joints with systemic clinical manifestations. It is basically Sero Positive RA & Sero Negative RA. (In Blood RA factor Positive, and Negative)

Study Design

Study Type
Interventional
Allocation
Na
Masking
None

Eligibility Criteria

Ages
18.00 Year(s) to 65.00 Year(s) (—)
Sex
All

Inclusion Criteria

  • Patients with clinical features of Amavata.
  • Patients of either gender, aged between
  • Patients who fulfill the revised criteria for Rheumatoid arthritis fixed by the American College of Rheumatology.
  • Patients of both RA factor positive and RA factor negative.
  • Patients who are willing to give consent form.
  • Patients who are eligible for kshara vasti.

Exclusion Criteria

  • Chronicity of more than 10 years.
  • Pregnant womens and lactating mothers.
  • Having severe crippling deformities.
  • Systemic diseases like uncontrolled Diabetes, Tuberculosis and Hypertension.

Outcomes

Primary Outcomes

To relieve the symptoms of Rheumatoid Arthritis and improve the quality of life

Time Frame: 90 days

Secondary Outcomes

  • to improve the quality of life by preventing disabilities(90 days)

Investigators

Sponsor
Dr. Kuncharapu Sandhya Rani
Sponsor Class
Other [self]
Responsible Party
Principal Investigator
Principal Investigator

Dr Kuncharapu Sandhya Rani

Dr. BRKR Govt Ayurvedic Medical college & Hospital

Study Sites (1)

Loading locations...

Similar Trials