Probiotic functionality of several probiotic supplements during gastro-intestinal transit in vivo in healthy human subjects

• Conditions: Metabolic syndrome; obesity; 10000546

• Registration Number: NL-OMON36265
• Lead Sponsor: niversiteit Maastricht

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 8

Inclusion Criteria

sex: male
age: 18-40 years
body mass index 18-30kg/m2

Exclusion Criteria

• History of severe cardiovascular, respiratory, urogenital, gastrointestinal/ hepatic, hematological/immunologic, HEENT (head, ears, eyes, nose, throat), dermatological/connective tissue, musculoskeletal, metabolic/nutritional, endocrine, neurological/psychiatric diseases, allergy, major surgery which might limit participation in or completion of the study protocol

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Sugar conversion. This by measuring:<br /><br>• Fructo- and Gluco-oligosaccharides<br /><br>• Mannitol<br /><br>• Sucrose<br /><br>• Fructose<br /><br>• Glucose</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>• Phenol red (marker for gastric emptying)<br /><br>• pH<br /><br>• Number of viable bacteria</p><br>