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临床试验/NCT07246824
NCT07246824招募中不适用

Expanding Access to Safe Water in Nigeria

University of Michigan1 个研究点 分布在 1 个国家目标入组 700 人开始时间: 2025年9月30日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
招募中
入组人数
700
试验地点
1
主要终点
Treat drinking water with chlorine (tested in water sample)

研究概览

简要总结

Access to safe water remains a pressing public health challenge in Nigeria, where 67% of the population lacks safely managed drinking water and waterborne diseases cause an estimated 70,000 child deaths annually. Building on evidence that point-of-use chlorination is highly cost-effective in reducing diarrheal disease, this study evaluates a scalable, community-based chlorine distribution model through a cluster-randomized controlled trial (RCT) in Kano State. Thirty communities across four Local Government Areas will be randomly assigned to one of three groups: (i) 20 treatment communities receiving community demonstrations and local chlorine redemption points, (ii) 10 control communities where no intervention will be conducted. After 3 months, 5 control communities will receive an individual-level sensitization and a voucher program and 5 will remain pure control communities. The RCT aims to estimate the causal impact of the community-based intervention on household chlorination rates, water quality (E. coli contamination), and knowledge of safe water practices over six months. By rigorously testing a community-led water treatment model, this study contributes new evidence on sustainable and cost-effective approaches to expand safe water access in low-resource settings. The results will inform national and regional strategies for scaling point-of-use chlorination across sub-Saharan Africa.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Prevention
盲法
None

入排标准

性别
Female
接受健康志愿者
是

入选标准

  • •Pregnant mothers and women with children under 5 children

排除标准

  • •Men, women with no children under 5 years old

研究组 & 干预措施

Treatment

Experimental

Community Demonstrations and Redemption Points

干预措施: Community Demonstrations (Behavioral)

Treatment

Experimental

Community Demonstrations and Redemption Points

干预措施: Redemption points (Behavioral)

Control

No Intervention

Neither community distributions will be conducted nor redemption points will be set-up during the study period

结局指标

主要结局

Treat drinking water with chlorine (tested in water sample)

时间窗: Measured up to 6 months of follow-up

Proportion of water samples with detectable chlorine in stored drinking water

次要结局

  • Treat drinking water with chlorine (self-reported)(Measured up to 6 months of follow-up)
  • Presence of E.coli(Measured up to 6 months of follow-up)
  • Level of E.coli(Measured up to 6 months of follow-up)
  • Unsafe risk of Coliform(Measured up to 6 months of follow-up)
  • Heard about chlorine(Measured up to 6 months of follow-up)
  • Ever used chlorine(Measured up to 6 months of follow-up)
  • Last used chlorine(Measured up to 6 months of follow-up)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Elisa Maria Maffioli

Assistant Professor

University of Michigan

研究点 (1)

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