An Observational Study to Investigate the Aerosol Particle Distribution During Aerosol Generating Procedures
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 15
- 试验地点
- 1
- 主要终点
- The virus load in the air sample pre procedure/treatment at 1 foot away from patient
研究概览
简要总结
Massive number of clinicians were infected during the outbreak of COVID-19, which raised the concerns of utilizing "aerosol generating procedures", particularly the use of high-flow nasal cannula, noninvasive ventilation, intubation, bronchoscopy examination and pulmonary function test. There appears to be a trend to avoid those treatments. Instead, aggressive intubation might cause shortage of medical devices and add extra workload. Therefore, we aimed to do a clinical observational study to evaluate the aerosol generation in these procedures and explore the potential measures to reduce the aerosol generation or dispersion.
详细描述
The intent is to monitor exhaled aerosol produced by COVID-19 patients pre and post aerosol generating procedures. Monitoring will occur at a distance of 1 and 3 feet from the subject's airway. This observational study will be conducted in standard patient hospital rooms (standard or negative pressure room).
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adult patients who are diagnosed as COVID-19 infection in ICU or Adult patients are indicated for pulmonary function tests
排除标准
- •No need for any respiratory therapy
结局指标
主要结局
The virus load in the air sample pre procedure/treatment at 1 foot away from patient
时间窗: 1 hour before procedure/treatment
The virus load in the air sample pre procedure/treatment at 1 foot away from patient's airway in the patient's room
The aerosol mass/count concentration and virus load in the air sample during procedure/treatment at 1 foot away from patient
时间窗: during procedure/treatment
The aerosol mass/count concentration and virus load in the air sample during procedure/treatment at 1 foot away from patient's airway in the patient's room
The aerosol mass/count concentration post procedure/ treatment at 1 foot away from patient
时间窗: 5 minutes post procedure/treatment
The aerosol mass/count concentration post procedure/ treatment at 1 foot away from HFNC in the patient's room
The aerosol mass/count concentration pre procedure/treatment at 3 feet away from patient
时间窗: 5 minutes before procedure/treatment
The aerosol mass/count concentration pre procedure/treatment at 3 feet away from patient's airway in the patient's room
The aerosol mass/count concentration pre procedure/treatment at 1 foot away from patient
时间窗: 5 minutes before procedure/treatment
The aerosol mass/count concentration pre procedure/treatment at 1 foot away from patient's airway in the patient's room
The virus load in the air sample during/after procedure/treatment at 1 foot away from patient
时间窗: 1 hour during/after procedure/treatment
The virus load in the air sample during/after procedure/treatment at 1 foot away from patient's airway in the patient's room
The aerosol mass/count concentration during procedure/ treatment at 3 feet away from patient
时间窗: during procedure/treatment
The aerosol mass/count concentration during procedure/ treatment at 3 feet away from HFNC in the patient's room
The aerosol mass/count concentration 5 mins post procedure/ treatment at 3 feet away from patient
时间窗: 5 minutes post procedure/treatment
The aerosol mass/count concentration 5 mins procedure/ treatment at 3 feet away from HFNC in the patient's room
次要结局
未报告次要终点