Implementation of a health education and risk prediction program for parents (WHeezing Illnesses STudy LEidsche Rijn (WHISTLER)-online) to reduce ineffective primary health care consumption for respiratory illnesses in children during the first year of life.

niversitair Medisch Centrum Utrecht0 sites700 target enrollmentTBD

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Not specified
Sponsor: niversitair Medisch Centrum Utrecht
Enrollment: 700
Status: Not yet recruiting
Last Updated: 2 years ago

Overview Investigators Eligibility Criteria Outcomes Similar Trials

Overview

Brief Summary

Koopman, L. P., Brunekreef, B., de Jongste, J. C. & Neijens, H. J. Definition of respiratory symptoms and disease in early childhood in large prospective birth cohort studies that predict the development of asthma. Pediatr Allergy Immunol 12, 118-124 (2001). 2. Kuehni, C. E., Davis, A., Brooke, A. M. & Silverman, M. Are all wheezing disorders in very young (preschool) children increasing in prevalence? Lancet 357, 1821-1825 (2001). 3. Fuhlbrigge, A. L. et al. The burden of asthma in the United States: level and distribution are dependent on interpretation of the national asthma education and prevention program guidelines. Am. J. Respir. Crit Care Med. 166, 1044-1049 (2002). 4. Guilbert, T. W. et al. Long-term inhaled corticosteroids in preschool children at high risk for asthma. N. Engl. J Med. 354, 1985-1997 (2006). 5. Johnston, S. L. Macrolide antibiotics and asthma treatment. J. Allergy Clin. Immunol. 117, 1233-1236 (2006). 6. Stein, R. T. & Martinez, F. D. Asthma phenotypes in childhood: lessons from an epidemiological approach. Paediatr. Respir. Rev. 5, 155-161 (2004). 7. Katier, N. et al. The Wheezing Illnesses Study Leidsche Rijn (WHISTLER): rationale and design. Eur. J. Epidemiol. 19, 895-903 (2004). 8. De Jong, B. M. et al. Determinants of health care utilization for respiratory symptoms in the first year of life. Med. Care 45, 746-752 (2007). 9. de Jong, B. M. et al. Respiratory symptoms in young infancy: child, parent and physician related determinants of drug prescription in primary care. Ref Type: Unpublished Work 10. Latzin, P. et al. Prospectively assessed incidence, severity, and determinants of respiratory symptoms in the first year of life. Pediatr. Pulmonol. 42, 41-50 (2007). 11. de Jong, B. M. et al. Respiratory symptoms in young infancy: child, parent and physician related determinants of drug prescription in primary care. Ref Type: Unpublished Work 12. de Jong, B. M. et al. Prediction of lower respiratory illness in the first year of life. 2008. Ref Type: Unpublished Work 13. Grimshaw, J. M. et al. Effectiveness and efficiency of guideline dissemination and implementation strategies. Health Technol. Assess. 8, iii-72 (2004). 14. Hunink, M. G. Outcomes research and cost-effectiveness analysis in radiology. Eur. J. Radiol. 27, 85-87 (1998). 15. Cohen, M. G. et al. A simple prediction rule for significant renal artery stenosis in patients undergoing cardiac catheterization. Am. Heart J. 150, 1204-1211 (2005). 16. Mokhlesi, B. et al. Predicting extubation failure after successful completion of a spontaneous breathing trial. Respir. Care 52, 1710-1717 (2007). 17. Verbeke, M., Schrans, D., Deroose, S. & De, M. J. The International Classification of Primary Care (ICPC-2): an essential tool in the EPR of the GP. Stud. Health Technol. Inform. 124, 809-814 (2006). 18. Osman, L. M., Baxter-Jones, A. D. & Helms, P. J. Parents' quality of life and respiratory symptoms in young children with mild wheeze. EASE Study Group. Eur. Respir. J. 17, 254-258 (2001). 19. WMA General Assembly. World medical association declaration of Helsinki. Ethical principles for Medical Research Involving Human Subjects. 2004. Tokyo. Ref Type: Report 20. Ministerie van justitie. Wet van 26 februari 1998, houdende regelen inzake medisch-wetenschappelijk onderzoek met mensen (Wet medisch-wetenschappelijk onderzoek met mensen). 1998. 's Gravenhage, De Minister van Justitie, W. Sorgdrager. Ref Type: Report 21. Federatie van medisch wetenschappelijke verenigingen. Code Goed Gebruik. Beknopte versie onderzoekers. 2002. Ref Type: Report 22. Federatie van medisch wetenschappelijke verenigingen. Gedragscode Gezondheidsonderzoek. Gedragscode van de Nederlandse biomedische onderzoeksgemeenschap goedgekeurd door het College Bescherming Persoonsgegevens in 2004. 2005. Zeist. Ref Type: Report 23. CCMO. CCMO-statement publicatiebeleid. 2002. Ref Type: Report 24. De, A. C. et al. Clinical trial registration: a statement from the International Committee of Medical Journal Editors. N. Engl. J. Med. 351, 1250-1251 (2004).

Registry

who.int

Start Date

TBD

End Date

TBD

Last Updated

2 years ago

Study Type

Interventional

Investigators

Sponsor

niversitair Medisch Centrum Utrecht

Eligibility Criteria

Inclusion Criteria

•Eligible for the study are families of healthy infants who participate in WHISTLER.

Exclusion Criteria

•Exclusion criteria for the WHISTLER\-study are gestational age \< 36 weeks, major congenital abnormalities and neonatal respiratory disease.
•Extra exclusion criteria for WHISTLER\-online are the absence of a computer or access to internet or the ignorance of using a computer or internet.