Association Between Body Roundness Index and Wound Healing Post-Thoracic Surgery: A Prospective Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 422
- 试验地点
- 1
- 主要终点
- Wound healing
研究概览
简要总结
Background Obesity is a significant risk factor for adverse postoperative outcomes, including impaired wound healing. This study aimed to investigate the association between the Body Roundness Index (BRI) and impaired wound healing following thoracic surgery.
Methods This study included 387 patients who underwent thoracic surgery at Tongji Hospital in Wuhan between October 2024 and January 2025. Wound healing was assessed 30 days postoperatively. Logistic regression and propensity score matching (PSM) analyses were performed to evaluate the relationship between BRI and impaired wound healing, with subgroup analyses conducted to further explore this association.
详细描述
This prospective cohort study collected clinical data from patients undergoing thoracic surgery at Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, between October 1, 2024, and January 30, 2025. Initial enrollment included 422 patients, with 387 participants retained after data cleaning (Figure 1). The primary objective was to evaluate the association between BRI and impaired postoperative wound healing through multivariable logistic regression, propensity score matching (PSM), and subgroup analyses.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 20 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- •Without surgery or transferred to other departments；
- •Missing basic information；
- •Failure to review on time or refusal to follow up；
- •Additional surgeries within 30 days of discharge from the hospital；
结局指标
主要结局
Wound healing
时间窗: From the day of surgery to 30 days postoperatively
Determine the presence of impaired wound healing based on the definitions and guidelines for wound assessment and evaluation of healing.
次要结局
未报告次要终点
研究者
Zhao bo
Professor
Tongji Hospital