TENDAI STUDY: Treatment to reduce depression and improve adherence to anti-retroviral therapy in Harare, Zimbabwe
- Conditions
- HIV/AIDS
- Registration Number
- PACTR201511001150307
- Lead Sponsor
- King's College London
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 60
1. Aged 18 or above
2. On ART for at least 4 months as confirmed by pharmacy records
3. Score ¿ 10 OR meet criteria for a diagnosis of depression on the 9 item Patient Health Questionnaire (PHQ-9) OR Score ¿ 9 on the Shona Symptom Questionnaire (SSQ-14)
4. Screen positive for recent non-adherence, as detected by any of the following methods:
i) Self Report Adherence Questionnaire
ii) Missed one HIV clinic appointment in the previous 6 months
iii) Falling CD4 count (CD4 below 350 that has fallen by at least 50 in the past 6 months)
iv) Detectable viral loads
1. Score ¿6 on the International HIV Dementia Scale (IHDS)
2. Score of 3 or higher for women and a score of 4 or higher for men on the short AUDIT-C screen for alcohol dependance
3. On medication for tuberculosis
4.Have suicidal intent as determined by the P4 Suicidality Screener
5. Interviewer assesses person too unwell and/ agitated to take part
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method