The effects of synbiotic supplementation on anti inflammatory index in lymphedema after breast cancer treatment
- Conditions
- ymphedema.
- Registration Number
- IRCT2017092023861N6
- Lead Sponsor
- Vice chancellor for research, Iran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- 88
Women with unilateral Breast Cancer Related Lymphedema; breast cancer lymphedema in STAGE = 2; age range of 18-60 years; BMI between 25 and 35; At least one month has passed since the last treatment such as radiotherapy; willingness to participate in the study Non-inclusion criteria: use of multi-vitamin minerals and omega-3 supplements up to 1 month before the study began; acute and chronic infection; history of autoimmune diseases such as rheumatoid arthritis; Inflammatory diseases such as heart failure, pulmonary, kidney and diabetes; taking supplements of probiotics from 6 months before study; having a weight loss diet in Length 6 months before the study; Smoking and alcohol consumption; Lymphedema due to other cancers Exclusion criteria : Unwillingness of the patient to continue research collaboration; No subsequent referral; Cancer recurrence during the study; Failure to follow a weight loss diet; Consumption of food and supplements containing probiotics during the study; Incidence of edema-like diseases such as renal, cardiovascular and respiratory failure during the study period; Metastasis; Infectious diseases in Study length; Consumption of less than 56 capsules of 70 capsules at the end of the study
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method IL-10. Timepoint: Before and after the intervention. Method of measurement: ELISA.
- Secondary Outcome Measures
Name Time Method