RBR-7m4v7b
Recruiting
Phase 2
A phase II randomized, double-blind, placebo controlled study of the safety and efficacy of ranitidine in diabetic patients with severe sepsis and septic shock.
Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo0 sitesJuly 30, 2018
Overview
- Phase
- Phase 2
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo
- Status
- Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Patient with age greater than 18 years; Admitted to the Emergency Unit of Clinical Hospital of Ribeirão Preto medical school of University of São Paulo (UE\-HCFMRP/USP); diagnosis of diabetes mellitus or serum glucose \> 200 mg / dL at the admission; diagnosis of severe sepsis or septic shock; ability of the patient or his or her legal representative to decide whether or not to participate in the survey before completing 48 hours of admission.
Exclusion Criteria
- •Septic Patients who do not have the criteria for severe sepsis or septic shock; continuous use of ranitidine or other H2 antagonist; hypersensitivity to ranitidine or other H2 blockers; pregnant women; participation in another study; diagnosis of HIV; realization of chemotherapy in the last 30 days; palliative care; lymphoproliferative disease; refusal to signing the consent form (CF) or not to participate in the study; need of procedure or examination with contrast which requires the use of ranitidine as premedication.
Outcomes
Primary Outcomes
Not specified
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