CTRI/2021/06/034308招募中未知
urse led Genetic Counselling in Improving Awareness and Implementation of screening services for hereditary womens cancer NuGenA - NuGenA
试验速览
- 阶段
- 未知
- 状态
- 招募中
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
入选标准
- •a) All non-mucinous epithelial ovarian cancer irrespective of their age
- •b) All first degree and second degree relatives of women diagnosed with
- •epithelial ovarian cancer and found to have deleterious mutation in BRCA1 or 2
- •c) If further funding is available: Then testing according to the NCCN guidelines
- •for Hereditary Breast and Ovarian cancer risk assessment
- •1. Personal history of breast cancer and ââ?°Â¥1 of these:
- •Ã¯â??· Diagnosed at age ââ?°Â¤45 years
- •Ã¯â??· Diagnosed at age ââ?°Â¥50 years with ââ?°Â¥1 close blood relatives with breast cancer at
- •age 50 years and/or ââ?°Â¥1 close blood relatives with epithelial ovarian cancer at
- •Ã¯â??· 2 breast primaries when first breast cancer diagnosis occurred at age ââ?°Â¤50 years
- •Ã¯â??· Diagnosed at age ââ?°Â¤60 years with a triple negative breast cancer
- •Ã¯â??· Diagnosed at age ââ?°Â¤50 years with a limited family history
- •Ã¯â??· Diagnosed at any age with ââ?°Â¥2 close blood relatives with pancreatic cancer at
- •Close male blood relative with breast cancer
- •Individual of ethnicity associated with higher mutation frequency (e.g.,
- •Ashkenazi Jewish)
- •Personal history of epithelial ovarian cancer
- •Ã¯â??· Personal history of male breast cancer
- •Personal history of pancreatic cancer at any age with ââ?°Â¥2 close blood relatives
- •with breast and/or ovarian cancer and/or pancreatic cancer at any age
- •2. No personal history of breast cancer, but ââ?°Â¥1 of these:
- •Ã¯â??· First- or second-degree blood relative meeting any of the above criteria
- •Third-degree blood relative with breast cancer and/or ovarian cancer with ââ?°Â¥2
- •close blood relatives with breast cancer (ââ?°Â¥1 with breast cancer at age ââ?°Â¤50
- •years) and/or ovarian cancer
排除标准
- •Any patient who does not meet the inclusion criteria
研究者
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