Feasibility Study: The Effect of Prazosin for Nighttime Symptoms of Civilian PTSD

Not Applicable

• Conditions: Stress Disorders, Post-Traumatic

• Registration Number: NCT00174551
• Lead Sponsor: Rainier Associates

Brief Summary

Investigating the effect of prazosin for nighttime symptoms of civilian Posttraumatic Stress Disorder.

Detailed Description

Each subject will receive prazosin and placebo trials, the order randomized. Day and nighttime symptoms will be monitored.

Study Timeline

• Study Start: 2003-11
• Status Verified: 2005-09
• Study First Submitted: 2005-09-09
• Study First Submitted QC: 2005-09-09
• Study First Posted: 2005-09-15
• Study Completion: 2005-11
• Last Update Submitted: 2006-09-07
• Last Update Posted: 2006-09-11

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

• must meet DSM-IV criterion for PTSD

Exclusion Criteria

• Must not have untreated sleep apnea

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Primary Outcome Measures

Name	Time	Method
Nightmare frequency
Sleep time
REM sleep time
CGI

Secondary Outcome Measures

Name	Time	Method
Distressed Awakenings frequency
PCL-C

Trial Locations

Locations (1)

Fletcher B. Taylor; 🇺🇸 Tacoma, Washington, United States