Effect of balloon volume and body position on oesophageal pressure manometry in critically ill children: a pilot study
- Conditions
- Acute lung injuryhealthy lungs10038716
- Registration Number
- NL-OMON46710
- Lead Sponsor
- niversitair Medisch Centrum Groningen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Withdrawn
- Sex
- Not specified
- Target Recruitment
- 50
* Informed consent
* Age younger than 12 years
* Need for mechanical ventilation for at least 24 hours
* Haemodynamically stable, assessed by the attending physician
* No informed consent
* Chronic respiratory failure on home ventilation
* Intracranial hypertension
* Bone marrow transplantation
* Immunocompromised patients (congenital or acquired)
* Pre-existing pulmonary hypertension
* Uncorrected congenital heart disease with left * to * right shunting or cyanotic heart disease
* Single ventricle laesions
* Evidence of esophageal pathology or the inability to pass a combined esophageal balloon/nasogastric feeding tube
* Contraindication to the passage of an esophageal pressure probe by either the oral or nasal route
* Withdrawal of life * sustaining treatment
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Peak-to-through oesophageal pressure at varying amounts of air in balloon</p><br>
- Secondary Outcome Measures
Name Time Method <p>a) Peak-to-through oesophageal pressure at varying amounts of air in balloon<br /><br>and body position (supine vs 30° upright)<br /><br>b) Difference in optimal balloon volume between children with and without lung<br /><br>injury</p><br>