Single centric non-randomized open clinical trial phase II in Vatha kalladaippu (Urolithiasis) with siddha medicine Vengara chunnam among patients attending OPD at Government Siddha Medical college Hospital,Chennai.
试验速览
- 阶段
- 2 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Reduction in clinical symptoms such as lower abdominal pain,oliguria,dysuria.
研究概览
简要总结
Urolithiasis is recurrent renal disease affecting 12% population in India. Urinary calculi consist of aggregates of crystals,usually containing calcium or phosphate in combination with small amount of proteins and glycoproteins.The most common types are calcium oxalate 60%,calcium phosphate 15%,struvite 15%,uric acid 10%,cysteine and others 1%.The predisposing factors are low urine volume,high ambient temperature,low fluid intake,high protein,high sodium excretion,high oxalate excretion,low citrate excretion,hypercalcemia of any cause.Renal stones vary greatly in size from sand like particles anywhere in the urinary tract to large round stones in the urinary bladder. In siddha system of medicine, there are unique combination of medicines that have solution to renal calculi. One such combination is VENGARA CHUNNAM which will be more effective and reliable. The method of preparation of medicine is easy and the raw drugs are also easily available.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •1.All gender 2.Age 18-60 years 3.Lower Abdominal pain 4.Flank pain 5.Burning Micturition 6.Oliguria 7.Haematuria 8.Presence of calculi of size 4-9mm.
排除标准
- •1.Stag horn calculus 2.Hydronephrosis 3.Cancer 4.Chronic kidney disease 5.Pregnancy 6.Lactating women.
结局指标
主要结局
Reduction in clinical symptoms such as lower abdominal pain,oliguria,dysuria.
时间窗: 90 days
次要结局
- Reduction in size of the stone(90 days)
研究者
Saranya N
Government Siddha Medical College, Arumbakkam, Chennai