Effectiveness of Combination Therapy of Microneedling and Minoxidil in Androgenetic Alopecia of Indonesian Men
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 入组人数
- 36
- 试验地点
- 1
- 主要终点
- Density of hair
研究概览
简要总结
The goal of this clinical trial is to compare the effectiveness of combination therapy of microneedling and minoxidil in androgenetic alopecia of Indonesian men. The main questions it aims to answer are:
- Is there an increase in hair density with combination therapy of microneedling and minoxidil versus minoxidil monotherapy?
- Is there an increase in hair diameter with combination therapy of microneedling and minoxidil versus minoxidil monotherapy?
Participants will be divided into 2 groups. The first one will receive minoxidil monotherapy, and the second one will receive a combination therapy of microneedling and minoxidil. Researchers will compare those 2 groups to see if there is a difference of effectiveness based on hair density and diameter.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 59 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •Indonesian
- •Age 18-59 years
- •Diagnosis of androgenetic alopecia
- •Hamilton-Norwood type III-IV
排除标准
- •Use of minoxidil or finasteride topical 1 month prior
- •Use of minoxidil or finasteride oral 1 month prior
- •Skin infection in the treatment area
- •Cosmetic procedures for the treatment of alopecia androgenetic such as platelet rich plasma, laser therapy,or microneedling 3 months prior
- •History of keloid
研究组 & 干预措施
Minoxidil 5% solution
Patients will receive minoxidil 5%, twice a day, for a total duration of 12 weeks.
干预措施: Minoxidil 5% Topical Solution (Drug)
Combination therapy of microneedling and minoxidil 5% solution
Patients will receive a combination therapy of microneedling and minoxidil 5%. Minoxidil 5%, will be given twice a day for a total duration of 12 weeks. The microneedling treatment will be given every 4 weeks (week 0, week 4, week 8)for a total duration of 12 weeks.
干预措施: Minoxidil 5% Topical Solution (Drug)
Combination therapy of microneedling and minoxidil 5% solution
Patients will receive a combination therapy of microneedling and minoxidil 5%. Minoxidil 5%, will be given twice a day for a total duration of 12 weeks. The microneedling treatment will be given every 4 weeks (week 0, week 4, week 8)for a total duration of 12 weeks.
干预措施: microneedling (Device)
结局指标
主要结局
Density of hair
时间窗: 12 weeks
Increase density of hair in alopecia androgenetic patient
Diameter of hair
时间窗: 12 weeks
Increase diameter of hair in alopecia androgenetic patient
次要结局
未报告次要终点