Pharmacy-based Interdisciplinary Program for Patients With Chronic Heart Failure
Not Applicable
Completed
- Conditions
- Chronic Heart Failure
- Registration Number
- NCT01692119
- Lead Sponsor
- Federal Union of German Associations of Pharmacists
- Brief Summary
The aim of the study is to investigate whether a continuous interdisciplinary intervention improves medication adherence (primary efficacy endpoint) and leads to a reduction of hospitalizations and mortality (primary safety endpoint) in elderly patients with chronic heart failure. The intervention, consisting of regular contacts with the local pharmacy and weekly dosing aids, aims to improve medication adherence and management.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 258
Inclusion Criteria
- Age: 60 years and older
- Chronic heart failure (CHF)
- Stable CHF medication including a diuretic
- Hospitalization for decompensated heart failure within past 12 months OR a value of ≥ 350 pg/mL for BNP or ≥ 1,400 pg/mL for NT-proBNP
- Written informed consent
Exclusion Criteria
- Use of a weekly dosing aid
- Unwillingness or inability to visit a participating pharmacy once a week
- Planned cardiac surgery
- Life-expectancy < 6 months
- Unwillingness or inability to comply with the study protocol (including drug abuse or alcohol dependency)
- Participation in other studies (currently or in the last 4 weeks)
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Medication Adherence 12 months Percentage of days covered (PDC) by prescribed medication and according to claims data
Days Lost Due to Unplanned Cardiovascular Hospitalizations or Death of Any Cause 12 months Days lost due to unplanned cardiovascular hospitalizations or death of any cause
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Saarland University
🇩🇪Homburg/Saar, Germany
Saarland University🇩🇪Homburg/Saar, Germany