Pharmacy-based Interdisciplinary Program for Patients With Chronic Heart Failure (PHARM-CHF): A Randomized Controlled Trial

Federal Union of German Associations of Pharmacists1 site in 1 country258 target enrollmentOctober 2012

ConditionsChronic Heart Failure

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Chronic Heart Failure
Sponsor: Federal Union of German Associations of Pharmacists
Enrollment: 258
Locations: 1
Primary Endpoint: Medication Adherence
Status: Completed
Last Updated: 5 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The aim of the study is to investigate whether a continuous interdisciplinary intervention improves medication adherence (primary efficacy endpoint) and leads to a reduction of hospitalizations and mortality (primary safety endpoint) in elderly patients with chronic heart failure. The intervention, consisting of regular contacts with the local pharmacy and weekly dosing aids, aims to improve medication adherence and management.

Registry

clinicaltrials.gov

Start Date

October 2012

End Date

March 2019

Last Updated

5 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

Federal Union of German Associations of Pharmacists

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•Age: 60 years and older
•Chronic heart failure (CHF)
•Stable CHF medication including a diuretic
•Hospitalization for decompensated heart failure within past 12 months OR a value of ≥ 350 pg/mL for BNP or ≥ 1,400 pg/mL for NT-proBNP
•Written informed consent

Exclusion Criteria

•Use of a weekly dosing aid
•Unwillingness or inability to visit a participating pharmacy once a week
•Planned cardiac surgery
•Life-expectancy \< 6 months
•Unwillingness or inability to comply with the study protocol (including drug abuse or alcohol dependency)
•Participation in other studies (currently or in the last 4 weeks)