Electronic Intervention for HIV Medication Adherence

Not Applicable

Completed

• Conditions: HIV
• Interventions: Behavioral: Life Steps for Medication Adherence

• Registration Number: NCT01291485
• Lead Sponsor: Oklahoma State University Center for Health Sciences

Brief Summary

The purpose of this study is to develop and examine the feasibility and initial efficacy of a computer-based intervention to improve medication adherence among people living with HIV.

Detailed Description

Not available

Study Timeline

• Study Start: 2011-01
• Study First Submitted: 2011-01-10
• Study First Submitted QC: 2011-02-07
• Study First Posted: 2011-02-08
• Primary Completion: 2011-09
• Study Completion: 2011-11
• Status Verified: 2012-10
• Last Update Submitted: 2012-10-09
• Last Update Posted: 2012-10-10

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 97

Inclusion Criteria

• infected with HIV
• over age 18
• currently prescribed a Highly Active Antiretroviral Therapy (HAART) regimen
• prescribed a regimen for the first time, changing regimens, or report adherence below 95% agree to brief follow-up interviews

Exclusion Criteria

• physical impairment that would prevent them from successfully completing the computer-based program (e.g., blind, deaf, severe neuropsychological impairment)
• Actively psychotic
• Not fluent in English

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Lifestyle counseling	Life Steps for Medication Adherence	Intervention includes education about HIV and medication adherence, motivational interviewing, cognitive behavioral techniques, and problem-solving strategies to improve HIV medication adherence and clinical outcomes.

Primary Outcome Measures

Name	Time	Method
HIV medication adherence	up to 6 months	Self-reported adherence to HIV medications will be assessed using the AACTG Medication Adherence Questionnaire (M. A. Chesney, et al., 2000).

Secondary Outcome Measures

Name	Time	Method
HIV Treatment Adherence Self-Efficacy	Baseline, 1-month, 3 months, and 6-months	Self-efficacy for adherence to HIV medications will be assessed using the HIV-ASES (Johnson et al., 2007). The HIV-ASES is a 12-item scale of patient confidence in their ability to carry out behaviors related to adhering to medication regimens. Responses range from 1 ("cannot do it at all") to 10 ("completely certain can do it"). Item scores are averaged with higher scores indicating higher adherence self-efficacy.
Quality of Life	Baseline, 1-month, 3-months, and 6-months	Quality of life will be assessed using the McGill Quality of Life questionnaire (S. Robin Cohen, Hassan, Lapointe, \& Mount, 1996). This instrument is a 16-item scale that assesses quality of life in four domains: physical well-being, psychological well-being, existential well-being, and support; each item is assessed on a 0-10 point scale.
Viral Load	Baseline, 1 month, 3 months, and 6 months
CD4 cell count	Baseline, 1 month, 3 months, and 6 months

Trial Locations

Locations (1)

Internal Medicine Specialty Services; 🇺🇸 Tulsa, Oklahoma, United States