Quadratus Lumborum Block Using Loss-of-resistance Versus Ultrasound-guided Technique
Trial Snapshot
- Phase
- Not Applicable
- Sponsor
- Cairo University
- Enrollment
- 16
- Locations
- 1
- Primary Endpoint
- Duration of analgesia
Study Overview
Brief Summary
This study aims to explore the feasibility of using loss-of-resistance technique for Quadratus Lumborum block (QLB). And to compare between the Ultrasound guided QLB type II and the loss-of-resistance technique for QLB as regards the degree and duration of analgesia and side effects.
Detailed Description
Quadratus lumborum block (QLB) is an abdominal plane block with increasing popularity. QLB is achieved by local anesthetic infiltration at the anterolateral aspect of quadratus lumborum muscle (QLB-I), or at the posterior aspect of the muscle (QLB-II), or transmuscular (QL-TM block). Ultrasound-guided technique is the usual route used for QLB performance. QLB had been considered a modification of transversus abdominis plane (TAP) block[4]. A cadaveric study had showed similar local anesthetic spread in both QL and TAP blocks.
TAP block could be performed by using either the ultrasound or loss-of-resistance technique; whilst, QLB is only performed using the ultrasound and the feasibility of loss-of-resistance technique had not been investigated for this block.
This study aims to explore the feasibility of using loss-of-resistance technique for QLB. And to compare between the Ultrasound guided QLB type II and the loss-of-resistance technique for QLB as regards the degree and duration of analgesia and side effects.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- Triple (Participant, Care Provider, Outcomes Assessor)
Eligibility Criteria
- Ages
- 18 Years to 65 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Patients scheduled for lower abdominal surgery under general anesthesia
Exclusion Criteria
- •Patient refusal to regional block,
- •Pregnancy
- •Coagulopathy
- •Cognitive impairment
- •Inflammation or infection at the puncture site
- •History of allergic reaction to study medications
Arms & Interventions
Loss-of-resistance
Patients in this group will receive Loss-of-resistance Quadratus lumborum block with 30 ml bupivacaine 0.25% in addition to general anesthesia.
Intervention: Loss-of-resistance Quadratus lumborum block (Procedure)
Loss-of-resistance
Patients in this group will receive Loss-of-resistance Quadratus lumborum block with 30 ml bupivacaine 0.25% in addition to general anesthesia.
Intervention: General anesthesia (Procedure)
Ultrasound-guided
Patients in this group will receive Ultrasound-guided Quadratus lumborum block type-II with 30 ml bupivacaine 0.25% in addition to general anesthesia.
Intervention: General anesthesia (Procedure)
Ultrasound-guided
Patients in this group will receive Ultrasound-guided Quadratus lumborum block type-II with 30 ml bupivacaine 0.25% in addition to general anesthesia.
Intervention: Ultrasound-guided Quadratus lumborum block (Procedure)
Outcomes
Primary Outcomes
Duration of analgesia
Time Frame: 24 hours
The time between the end of the surgery and the first analgesia request
Secondary Outcomes
- Postoperative morphine consumption(24 hours)
- Intraoperative extra-analgesia requirements(3 hours)
- visual analogue pain score at rest to assess the pain severity(24 hours)
- Visual analogue pain score at movement to assess the pain severity(24 hours)
- Systolic blood pressure(24 hours)
- Heart rate(24 hours)
Investigators
Ahmed Hasanin
Assistant professor
Cairo University