Soy Fiber Improves Weight Loss and Lipid Profile

Not Applicable

Completed

• Conditions: Obesity; Weight Loss; Overweight
• Interventions: Dietary Supplement: biscuits supplemented with soy fiber

• Registration Number: NCT01802840
• Lead Sponsor: Zhejiang University

Brief Summary

The aim of this study is to examine the effects of soy fiber on body weight, body composition and blood lipids in overweight and obese participants.

Detailed Description

Thirty nine overweight and obese college adults (19-39 y of age) were randomly assigned to consume control biscuits or biscuits supplemented with soy fiber for 12 wk (approximately 100g/d). Information on body weight, body mass index, waist/hip circumference, blood pressure as well as measures of lipoprotein, glucose concentrations, and HbA1c was obtained at baseline, 8 and 12 wk after intervention. Body composition was also assessed at baseline and wk 12, respectively.

Study Timeline

• Study Start: 2012-03
• Primary Completion: 2012-06
• Study Completion: 2012-07
• Study First Submitted: 2013-02-23
• Study First Submitted QC: 2013-02-28
• Study First Posted: 2013-03-01
• Status Verified: 2022-07
• Last Update Submitted: 2022-07-01
• Last Update Posted: 2022-07-07

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 39

Inclusion Criteria

• BMI of 23-35 kg/m2

Exclusion Criteria

• Subjects taking any drugs, botanicals or nutraceutical known to influence body weight or blood pressure
• significant history of eating disorders
• strenuous exercise to lose weight
• lipid-lowering medication
• use of steroids and other agents that may influence lipid metabolism
• hyperlipidemia
• hyperglycemia
• diabetes mellitus
• cardiovascular disease
• major systemic diseases
• gastrointestinal problems
• liver and renal failure

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
biscuits without soy fiber	biscuits supplemented with soy fiber	biscuits without soy fiber
biscuits supplemented with soy fiber	biscuits supplemented with soy fiber	biscuits supplemented with soy fiber

Primary Outcome Measures

Name	Time	Method
weight loss	12 weeks	Body weight of participants in soy fiber group was decreased significantly over the study period compared with the baseline.

Secondary Outcome Measures

Name	Time	Method
serum levels of low density lipoprotein cholesterol	12 weeks	Serum levels of low density lipoprotein cholesterol of participants in soy fiber group was decreased significantly over the study period compared with the baseline.
body fat	12 weeks	Body fat of participants in soy fiber group was lowered significantly at wk 12 than that of baseline.
serum levels of total cholesterol	12 weeks	Serum levels of total cholesterol of participants in soy fiber group was decreased significantly over the study period compared with the baseline.

Trial Locations

Locations (1)

Zhejiang University; 🇨🇳 Hangzhou, Zhejiang, China