Soy Fiber Improves Weight Loss And Lipid Profile In Overweight And Obese Adults: A Randomized Controlled Trial
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Enrollment
- 39
- Locations
- 1
- Primary Endpoint
- weight loss
Study Overview
Brief Summary
The aim of this study is to examine the effects of soy fiber on body weight, body composition and blood lipids in overweight and obese participants.
Detailed Description
Thirty nine overweight and obese college adults (19-39 y of age) were randomly assigned to consume control biscuits or biscuits supplemented with soy fiber for 12 wk (approximately 100g/d). Information on body weight, body mass index, waist/hip circumference, blood pressure as well as measures of lipoprotein, glucose concentrations, and HbA1c was obtained at baseline, 8 and 12 wk after intervention. Body composition was also assessed at baseline and wk 12, respectively.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Basic Science
- Masking
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
Eligibility Criteria
- Ages
- 19 Years to 39 Years (Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •BMI of 23-35 kg/m2
Exclusion Criteria
- •Subjects taking any drugs, botanicals or nutraceutical known to influence body weight or blood pressure
- •significant history of eating disorders
- •strenuous exercise to lose weight
- •lipid-lowering medication
- •use of steroids and other agents that may influence lipid metabolism
- •hyperlipidemia
- •hyperglycemia
- •diabetes mellitus
- •cardiovascular disease
- •major systemic diseases
- •gastrointestinal problems
- •liver and renal failure
Outcomes
Primary Outcomes
weight loss
Time Frame: 12 weeks
Body weight of participants in soy fiber group was decreased significantly over the study period compared with the baseline.
Secondary Outcomes
- serum levels of low density lipoprotein cholesterol(12 weeks)
- body fat(12 weeks)
- serum levels of total cholesterol(12 weeks)
Investigators
Xiaojie Hu
Msd
Zhejiang University