All the Phases Study Will be Operated by the Department of Hepatobiliary Surgery, The Affiliated Hospital of Guiyang Medical College
试验速览
- 阶段
- 4 期
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- The contraction function of the gallbladder
研究概览
简要总结
To explore the therapeutic effects for treatment of cholecystolithiasis by minimally invasive cholecystolithotomy with gallbladder reservation and laparoscopic cholecystectomy. Method： patients with cholecystolithiasis who received minimally invasive Cholecystolithotomy with gallbladder reservation and patients with cholecystolithiasis who received laparoscopic cholecystectomy(LC) in The Affiliated Hospital of Guiyang Medical College from May 2011 to December 2013. Patients who received minimally invasive cholecystolithotomy with gallbladder reservation as trial group, patients who received LC as control group.the overall follow-up period is 1 year. Then the investigators statistically analyze improvement of cholecystolithiasis symptoms in every group, thickness of gall bladder wall, the gallbladder function and the rate of the recurrence of cholesterol gallstone in trial group.
详细描述
The investigators Prospect： Minimally invasive cholecystolithotomy with gallbladder reservation is meaningful for recovering the function of gallbladder.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 12 Years 至 75 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Clinical diagnosis of calculous cholecystitis.
排除标准
- •Gallbladder's wall >3mm, atrophied gallbladder,gallstone obstruct the Hartmann's pouch.
- •Abdominal ultrasound display the contractibility of gallbladder is poor.
- •The aged patients with bad heart and lung function.
- •Patients who has acute cholecystitis,pancreatitis,pancreaticobiliary diseases, especially choledocholithiasis.
- •Pregnant or lactational women.
研究组 & 干预措施
gallbladder reservation
Patients in trial group all took minimally invasive cholecystolithotomy with gallbladder reservation
干预措施: minimally invasive cholecystolithotomy with gallbladder reservation (Procedure)
laparoscopiccholecystectomy
Patients in control group all received LC.
干预措施: laparoscopic cholecystectomy (Procedure)
结局指标
主要结局
The contraction function of the gallbladder
时间窗: Participants will be followed for overall 1 year after surgery
Measure the participants' contraction function of gallbladder by the trial for contraction function of gallbladder
次要结局
- The thickness of gallbladder wall(Participants will be followed for overall 1 year after surgery)
研究者
Chengyi Sun
Department of Hepatobiliary Surgery
The First Affiliated Hospital of Guangzhou Medical University