NCT00640952撤回不适用
Acamprosate for Treatment of Compulsive Behaviors and Craving in Parkinson's Disease
适应症
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 试验地点
- 2
- 主要终点
- safety and efficacy compared to baseline scores
研究概览
简要总结
The purpose of this study is to determine how many patients with Parkinson's disease have compulsive behaviors, and what types of behaviors they have. This study will also determine if acamprosate can be used to treat compulsive behaviors in Parkinson's disease patients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Idiopathic Parkinson's disease
- •Active dopaminergic therapy at stable dose for one month (levodopa or dopamine agonist)
- •Able and willing to complete Rating Scales
- •Presence of one or more compulsive behavior based on responses to Rating Scales (defined as >5 on the SOGS; >17 on the YBOCS-SV and YBOCS-CUV; >1.7 on the SCS for women and >2.1 on the SCS for men; >15 on the YBOCS-BE, >5.5 on the CQ).
- •Written informed consent
- •Inclusion criteria (controls):
- •No significant psychiatric disease
- •Able and willing to complete Rating Scales
- •Written informed consent
排除标准
- •No anticipated need for adjustment of medications for Parkinson's disease
- •Current participation in another clinical study
- •History of unstable psychiatric disease (as determined by the Principal Investigator)
- •Women of childbearing age not using appropriate contraceptive methods (oral contraceptives, condoms, surgery)
结局指标
主要结局
safety and efficacy compared to baseline scores
时间窗: 6 months
次要结局
- change from baseline assessment tools used in the study(6 months)
研究者
Joohi Jimenez-Shahed
Principal Investigator
Baylor College of Medicine
研究点 (2)
Loading locations...
相似试验
已完成
不适用
Augmentation in Tx-resistant OCD: an Open Label TrialObsessive Compulsive DisorderNCT00590642Creighton University30
已完成
不适用
Neural Correlates of CompulsivityObsessive-Compulsive DisorderNCT05195476Columbia University41
已完成
2 期
Tolcapone in Obsessive Compulsive DisorderObsessive-Compulsive DisorderNCT03348930University of Chicago20
已完成
4 期
Escitalopram for the Treatment of Obsessive Compulsive Disorder (OCD)Obsessive Compulsive DisorderNCT00116532Massachusetts General Hospital30
已完成
不适用
Predicting Medication Response in Obsessive Compulsive DisorderObsessive Compulsive DisorderNCT01404871Sunnybrook Health Sciences Centre26