Internetförmedlad Kognitiv Rehabilitering Vid Lindrig Kognitiv störning
试验速览
- 阶段
- 不适用
- 状态
- Enrolling By Invitation
- 发起方
- 入组人数
- 64
- 试验地点
- 1
- 主要终点
- Mayo Portland Adaptability Inventory - fourth edition (MPAI-4), Participation subscale
研究概览
简要总结
Acquired brain injury and neurological disorders cause cognitive deficits, which in turn cause reduced participation in everyday life. Cognitive rehabilitation, where patients learn about cognition, cognitive deficits and ways to circumvent problems arising from deficits can increase participation and quality of life. ERehabCog is an internet delivered cognitive rehabilitation program intended for patients suffering mild to moderate impairments. The program consists of information and homework assignments, which take approximately 10 weeks to complete with the assistance of a therapist. Effects are evaluated through measures of everyday life participation, mood, and life satisfaction and compared with an attention training program. This study aims to contribute to the evidence base for internet delivered cognitive rehabilitation for mild to moderate cognitive impairments. Evidence based interventions are vital to use the potential of technology to the benefit of affected patients.
详细描述
When broadly defined, diseases and injuries affecting the central nervous system are one of the leading causes of disease burden in the world affecting more than 3 billion people. With such a large proportion of the global population affected, optimization of limited resources in the form of specialized rehabilitation is instrumental to ensuring sustainable public health.
The consequences of acquired brain injuries (ABIs) and neurological disorders are multifaceted, causing diminished functional capacity in a range of areas. Cognitive impairments are common, affecting ability to work, take on reponsibilities at home and in the community. Relationships in all significant life areas can be disrupted. As a result, patients may experience a significant shift in a plurality of life roles. Rehabilitation aims to help patients recapture premorbid capacities and reduce the impact of deficits while considering the needs and context of the patient. Cognitive rehabilitation has the potential to ameliorate patient outcomes. Patients in Sweden are offered cognitive rehabilitation as a part of multimodal rehabilitation programs, typically provided in university hospital settings. The demand for such interventions is greater than the amount provided. Patients with mild cognitive deficits are generally less prioritized than those with greater impairments. Internet provided rehabilitation programs can increase the accessibility of cognitive rehabilitation.
eRehabCog is an internet-delivered 10 module cognitive rehabilitation program designed to aid patients experiencing mild to moderate cognitive deficits following acquired brain injury or neurological disorders. The philosophy behind the development of eRehabCog is grounded in a compensatory-metacognitive approach. That is to say, patients learn about cognitive functions, consequences of deficits and ways to compensate. This approach has both a practical component where patients learn strategies they may use in their everyday life and a self-reflective component where patients learn to think about their thinking in such a way to raise their awareness of their functioning.
CogMed QM is a 10 week digital working memory training program which has been evaluated in children with ADHD and adults with stroke, showing improvements in working memory function. CogMed QM is a restitutive training program, intended to help patients retake diminished working memory capacity.
The overall aim of this study is to evaluate the efficacy of eRehabCog for patients experiencing mild to moderate cognitive deficits. Specific aims are to 1) evaluate the efficacy of eRehabCog for patients with ABI and ND admitted to community neurorehabilitation 2) compare the effects of eRehabCog to CogMed QM
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Enrolled in community neurorehabilitation in Stockholm, Sweden
- •Mild to moderate cognitive impairment as a consequence of acquired brain injury or nervous system disease
- •MoCA 21 ≥
- •Sufficient command of Swedish language
- •Access to internet connected device and internet connection
排除标准
- •Severe and enduring psychiatric or behavioural disorders (i.e Schizophrenia, substance abuse)
- •Suspected or diagnosed dementia
- •Homelessness or other social instability rendering access to internet unpredictable
研究组 & 干预措施
eRehabCog
10 week (1 hour / week, 10 hours in total) internet delivered manualised cognitive rehabilitation
干预措施: eRehabCog (Behavioral)
CogMed QM
5 week (2 hours / week, 10 hours in total) internet delivered working memory training program
干预措施: CogMed QM (Behavioral)
结局指标
主要结局
Mayo Portland Adaptability Inventory - fourth edition (MPAI-4), Participation subscale
时间窗: Two weeks before intervention, at intervention start, at the end of treatment at 10 weeks, at six months post intervention ed
Change in T-score
次要结局
- MPAI-4 Adaptability subscale(Two weeks before intervention, at intervention start, at the end of treatment at 10 weeks, at six months post intervention ed)
- MPAI-4 Abilities subscale(Two weeks before intervention, at intervention start, at the end of treatment at 10 weeks, at six months post intervention ed)
- MPAI-4 Total score(Two weeks before intervention, at intervention start, at the end of treatment at 10 weeks, at six months post intervention ed)
- Hospital Anxiety and Depression Scale(Two weeks before intervention, at intervention start, at the end of treatment at 10 weeks, at six months post intervention ed)
- Life Satisfaction Questionnaire (LiSat-11)(Two weeks before intervention, at intervention start, at the end of treatment at 10 weeks, at six months post intervention ed)
- Community Integration Questionnaire - Revised (CIQ-R)(Two weeks before intervention, at intervention start, at the end of treatment at 10 weeks, at six months post intervention ed)
研究者
Aniko Bartfai
senior professor in neuropsychology, Karolinska Institutet
Danderyd Hospital