Strict Glycemic Control by Insulin Infusion:Observations on Emergency Department Initiation
- Registration Number
- NCT00779701
- Lead Sponsor
- Temple University
- Brief Summary
Glycemic control can be safely achieved in surgical and medical intensive care unit settings and has been shown to improve short and long-term clinical outcomes. As such, insulin infusion protocols are routinely used in the ICU setting. The investigators plan to establish the use of strict glycemic control in a heterogenous group of acutely ill patients in the ED setting. The investigators propose to study the aspects of implementing a strict glycemic control protocol in the ED.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 27
Inclusion Criteria
- Patients with blood glucose ≥130 mg% considered to be critically ill as defined by:
APACHE II score ≥9 (See Appendix 1) OR >2 SIRS criteria with lactate ≥ 4 or BP < 90mmHg despite one liter of fluid OR Evidence of Organ Dysfunction (see Appendix 1)
Exclusion Criteria
- Patients requiring urgent interventional procedure (e.g. cardiac catheterization, dialysis) or surgery performed outside of the ED.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description A Insulin All subjects placed on insulin infusion.
- Primary Outcome Measures
Name Time Method Time to Achieve Glycemic Control Study duration 6 hours. Blood glucose checked at 30 minutes then every 15 minutes until within target blood glucose range then every hour.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Temple University Hospital
🇺🇸Philadelphia, Pennsylvania, United States