Natural History Study of Retinitis Pigmentosa Type 11

Active, not recruiting

• Conditions: Retinitis Pigmentosa; Retinitis Pigmentosa 11

• Registration Number: NCT04805658
• Lead Sponsor: Oslo University Hospital

Brief Summary

Observational study of patients with retinitis pigmentosa type 11

Detailed Description

Natural history study with clinical examination every 6 months.

Study Timeline

• Study Start: 2021-02-01
• Study First Submitted: 2021-03-16
• Study First Submitted QC: 2021-03-16
• Study First Posted: 2021-03-18
• Status Verified: 2024-04
• Last Update Submitted: 2025-03-18
• Last Update Posted: 2025-03-21
• Primary Completion: 2028-04-01
• Study Completion: 2028-04-01

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• Clinical diagnosis of retinitis pigmentosa caused by a disease-causing mutation involving the PRPF31 gene
• Or disease-causing mutation involving the PRPF31 gene without the clinical diagnosis of retinitis pigmentosa

Exclusion Criteria

• Under 18 years
• Other types of retinitis pigmentosa

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Progression of disease	24 mounths	Retinal function measured by functional and structural testing

Trial Locations

Locations (1)

Department of Ophthalmology, Oslo University Hospital; 🇳🇴 Oslo, Norway