Natural History Study of Retinitis Pigmentosa Type 11
Active, not recruiting
- Conditions
- Retinitis PigmentosaRetinitis Pigmentosa 11
- Registration Number
- NCT04805658
- Lead Sponsor
- Oslo University Hospital
- Brief Summary
Observational study of patients with retinitis pigmentosa type 11
- Detailed Description
Natural history study with clinical examination every 6 months.
Recruitment & Eligibility
- Status
- ACTIVE_NOT_RECRUITING
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
- Clinical diagnosis of retinitis pigmentosa caused by a disease-causing mutation involving the PRPF31 gene
- Or disease-causing mutation involving the PRPF31 gene without the clinical diagnosis of retinitis pigmentosa
Exclusion Criteria
- Under 18 years
- Other types of retinitis pigmentosa
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Progression of disease 24 mounths Retinal function measured by functional and structural testing
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie RP11 progression in NCT04805658 observational study?
Are there specific biomarkers for RP11 patient stratification in natural history studies?
How does RP11 disease progression compare to other retinitis pigmentosa subtypes?
What are the potential therapeutic targets identified in RP11 natural history studies?
What adverse events are associated with RP11 and how are they managed in clinical research?
Trial Locations
- Locations (1)
Department of Ophthalmology, Oslo University Hospital
🇳🇴Oslo, Norway
Department of Ophthalmology, Oslo University Hospital🇳🇴Oslo, Norway