Effect of Zamzam Water on Streptococcus Mutans and Oral pH in High Caries-Risk Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 36
- 试验地点
- 2
- 主要终点
- Salivary PH level
研究概览
简要总结
The present study aims to evaluate and compare the effect of Zamzam water as mouthwashes in high caries-risk patients regarding:
i. Streptococcus mutans (S. mutans) count. ii. Oral pH. After 3 and 6 months interval.
详细描述
The present study aims to evaluate and compare the effect of Zamzam water mouthwashes in high caries-risk patients regarding:
i. Streptococcus mutans (S. mutans) count. ii. Oral pH. all patients will be into two groups; The first group will use Zamzam water mouthwash for a six months with other preventive protocols including fissure sealants and preventive restorations wherever needed, while the second group will undergo preventive protocols only. During these six months, patients will be reassessed at three and six-month intervals regarding S. mutans count, oral pH, and caries risk level.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Triple (Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 35 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Male or female participants aged between 18-35 years.
- •Systemically- free individuals.
- •High caries-risk patients according to ADA (American Dental Association).
- •Not on a medication interfering with salivary secretion.
- •Co-operative patients approved to participate in the study.
排除标准
- •Patients who are already on any mouthwash regime.
- •Patients who are on any medication that would alter the salivary secretion.
- •Allergy to any of the ingredients of the study products.
结局指标
主要结局
Salivary PH level
时间窗: 3 months and 6 months
using pH meter
caries risk level
时间窗: 3 months and 6 months
According to ADA
Streptomutans count
时间窗: 3 months and 6 months
measurements of Colony forming unit (CFU) will be performed using blood agar and mitis salivarius-bacitracin agar (MSBA).
次要结局
未报告次要终点
研究者
Reham Youssef
Principal Investigator
Al-Azhar University