Treatment of obstructive sleep apnea and rehabilitation outcome in stroke
- Conditions
- obstructive sleep apnea syndrome (OSAS)sleep disordered breathing (SDB)1000796310046304
- Registration Number
- NL-OMON36215
- Lead Sponsor
- Heliomare
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 140
First-time stroke confirmed by neurological assessment and CT-scan or MRI-scan
Baseline measurement (T<=0) between 1 to 16 weeks after stroke
Able to cooperate with SAS screening and neuropsychological assessment
Informed consent for study participation
18-85 years of age
Obstructive or mixed SAS (for intervention part of the study)
Severe unstable medical conditions
Severe cardiac problems (like angina pectoris or pacemaker/ventricular impairments)
Severe pulmonal disease (severe dyspnea of effort or severe pulmonal emphysema)
Severe aphasia or confusion, which could strongly influence the performance on the neuropsychological assessment
Severe psychiatric or somatic comorbidity, which could strongly influence the performance on the neuropsychological assessment
Central SAS only
Severe OSAS (AHI>60 in combination with desaturations below 70%), which could endanger patient's health if CPAP treatment is not immediately started
Obesity hypoventilation syndrome
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The primary study parameters are cognitive and functional outcome. </p><br>
- Secondary Outcome Measures
Name Time Method <p>Secondary measures are fatigue, mood and sleep quality. Sociodemographic and<br /><br>clinical data, CPAP compliance, nocturnal arousal and rehabilitation therapy<br /><br>will be included as control measures.</p><br>