ACTRN12615000106538尚未招募未知
Efficacy and safety of artemisinin-based combination therapy: artesunate-amodiaquine (ASAQ) and artemether-lumefantrine (AL) in the treatment of uncomplicated falciparum malaria in 4 provinces of Burundi
适应症
试验速览
- 阶段
- 未知
- 状态
- 尚未招募
- 入组人数
- 528
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 6 Months 至 10 Years（—）
- 性别
- All
入选标准
- •children aged 6 months to 10 years
- •monoinfection with P falciparum confirmed by microscopy
- •parasitemia between 1000-200000 parasites (asexual) per microliter
- •fever (equal or greater than 37.5 celsius) or history of fever within past 24 hours
- •able to swallow oral medication
- •ability and willingness to follow protocol procedures and schedule of assessments
- •written informed consent from parent or guardian
排除标准
- •presence of danger and signs of severe malaria
- •mixed infection or infection of than P. falciparum detected by microscopy
- •severely malnourished
- •fever due to other diseases (measles, acute lower respiratory tract infection, severa diarrhea); chronic or severe hepatic, renal or cardiac diseases; HIV/AIDS
- •clinical signs of acute jaundice
- •abnormal level of granulocytes or liver transaminases
- •regular medication that could interfere with antimalarial pharmacokinetics;
- •history of hypersensitivity reactions or contraindications to any medicines being used
研究者
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