The prediction of short-term and long-term treatment response to sertraline in panic disorder

Completed

• Conditions: Panic disorder; Mental and Behavioural Disorders; Anxiety disorders

• Registration Number: ISRCTN03447252
• Lead Sponsor: niversity Medical Center Groningen (The Netherlands)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2006-11-22
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 57

Inclusion Criteria

1. Panic Disorder According to Diagnostic and Statistical Manual of mental disorders (DSM-IV)
2. Two panic attacks in medication-free run-in period
3. Outpatients more than 18 years

Exclusion Criteria

1. Co-morbid psychotic disorder, alcohol abuse, major affective disorder or personality disorder in the last year
2. Participation in other drug trial 30 days prior to selection
3. Serious medical illness
4. History of hepatitis
5. Risk of suicidality
6. History of drug allergy of hypersensitivity to SSRIs
7. Pregnancy, lactation or childbearing potential during the study

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To identify variables mentioned above (at baseline) that can predict short-term and long-term response to treatment with sertraline in Panic Disorder.

Secondary Outcome Measures

Name	Time	Method
1. To establish whether Autonomous Nervous System (ANS) functioning is a state marker of illness severity.<br>2. To establish whether treatment with sertraline has an affect on the functioning of the ANS.