Change of Neural Network Indicators Through Narrative Treatment of PTSD in Torture Victims
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- PTSD diagnosis and severity score according to the Clinicians Administered PTSD Scale (CAPS)
研究概览
简要总结
Effective Treatment of PTSD involves talking about the traumatic event in detail.It is unclear how this process influences the sensory-specific trauma network (fear structure)in the traumatized person. The goal of the project is to test the hypothesis that treatment-facilitated recovery does not change the original fear structure but establishes an inhibitory mechanism that depends on verbal activity. An affective visual steady-state paradigm in magnetencephalography (MEG) using positive, aversive and neutral picture stimuli will be used to examine the spatial and temporal pattern of the processing of emotional stimuli. To examine the effects of treatment this paradigm will be used as outcome measure within a randomized controlled trial of Narrative Exposure Therapy and a waiting-list control condition for severely traumatized torture victims.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 65 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •experiences of organized violence/torture
- •PTSD diagnosis
排除标准
- •psychotic disorder
- •neurological disease or seizures
- •current drug/alcohol abuse
研究组 & 干预措施
A
Narrative Exposure Therapy (NET)
干预措施: NET (Behavioral)
B
Waitinglist Control Group
结局指标
主要结局
PTSD diagnosis and severity score according to the Clinicians Administered PTSD Scale (CAPS)
时间窗: 4 & 9 months after completion of treatment
次要结局
- steady state visual evoked magnetic fields in response to affective stimuli(4 & 9 months after completion of treatment)
