A Retrospective Study on Extranodal Lymphoma or Lymphoma of Rare Pathological Types
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Lymphoma
- Sponsor
- Ruijin Hospital
- Enrollment
- 10000
- Locations
- 1
- Primary Endpoint
- Overall Survival (OS)
- Status
- Not yet recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
The aim of this study is to retrospectively collect clinical information on patients with extranodal or rare lymphomas, and to explore the best treatment strategy for these lymphomas in the real-world population.
Detailed Description
Lymphoma is a highly common malignant tumor in Asia. For specific extra-abdominal sites or rare pathological subtypes of lymphoma, traditional chemotherapy protocols often cannot provide satisfactory results for patients. This study aims to retrospectively collect clinical information on patients with extranodal lymphoma or rare pathological subtype lymphoma, including the distribution of involved sites, clinical and molecular characteristics of different lymphoma subtypes, clinical treatment protocols, and prognosis, to explore the best treatment strategy for these lymphomas in the real-world population.
Investigators
Zhao Weili
Prof.
Ruijin Hospital
Eligibility Criteria
Inclusion Criteria
- •Age ≥ 18 years (including 18 years old).
- •Patients newly diagnosed with non-Hodgkin lymphoma with extranodal involvement, whether it is primary, secondary, or cannot be determined; Or patients newly diagnosed with non-Hodgkin lymphoma of rare pathological types, including IVLBCL, SMZL, ALCL, AITL, MALTL.
- •Patients who have received systematic clinical treatment.
- •Patients with measurable lesions, at least containing one effective evaluation of efficacy.
Exclusion Criteria
- •Patients who only receive supportive treatment.
- •Patients who cannot obtain effective evaluation data of efficacy.
Outcomes
Primary Outcomes
Overall Survival (OS)
Time Frame: Baseline up to data cut-off (up to approximately 1 year)
Overall Survival (OS) will be defined from the start date of therapy to the date of death from any cause.
Progression Free Survival (PFS)
Time Frame: Baseline up to data cut-off (up to approximately 1 year)
Progression-Free Survival (PFS) will be defined from the date of starting therapy and the date of disease progression, relapse or death from any cause.
Secondary Outcomes
- Clinical characteristics form(Baseline up to data cut-off (up to approximately 1 year))
- Biological characteristics form(Baseline up to data cut-off (up to approximately 1 year))