The effect of oral black seed oil on knee osteoarthritis

Phase 2

Recruiting

• Conditions: Knee osteoarthritis.; Osteoarthritis, unspecified site; M19.9

• Registration Number: IRCT20210923052559N1
• Lead Sponsor: Mashhad University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 21 November 2022

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

Knee osteoarthritis
Satisfaction to enter the study

Exclusion Criteria

Taking medicine for osteoarthritis of the knee
Having an infection or primary inflammatory disease in the knee joint
Arthritis caused by crystals
Intra-articular tumors
Knee joint ligament instability
Previous intra-articular fracture
Knee joint surgery (arthroscopic or otherwise) in the last 12 months
Injection of any intra-articular drug in the last 3 months
Existence of simultaneous severe diseases (metabolic diseases and history of stroke in the past)

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The amount of pain in the knee area. Timepoint: At the beginning of the study (before the start of the intervention) and 1, 2 and 3 months after the start of black seed oil capsules. Method of measurement: WOMAC questionnaire.;Tenascin-C serum level. Timepoint: At the beginning of the study (before the start of intervention) and 3 months after the start of taking black seed oil capsules. Method of measurement: ELISA method using the Tenascin-c kit from Zellbio GmbH company.