Antro-pyloro-duodenal Motility in Idiopathic Gastroparesis

Completed

• Conditions: Gastroparesis

• Registration Number: NCT01519180
• Lead Sponsor: University Hospital, Rouen

Brief Summary

Impaired gastric emptying may cause dyspeptic symptoms including nausea, vomiting and even nutritionnal impairment. Delay in gastric emptying may result from antro-pyloro-duodenal motility impairement.

Detailed Description

The aim of this study is therefore to measure antro-pyloro-duodenal motor activity in patients with idiopathic gastroparesis.

Study Timeline

• Study Start: 2012-01
• Study First Submitted: 2012-01-18
• Study First Submitted QC: 2012-01-25
• Study First Posted: 2012-01-26
• Primary Completion: 2014-01
• Study Completion: 2014-01
• Status Verified: 2014-09
• Last Update Submitted: 2014-09-05
• Last Update Posted: 2014-09-08

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 32

Inclusion Criteria

• Idiopathic gastroparesis or healthy volunteers
• Idiopathic gastroparesis must have delayed gastric emptying shown using C13 breath test

Exclusion Criteria

• Diabetic or post-surgical gastroparesis
• Treatment modifying GI motility (prokinetics, opioids...)
• Parkinson or neurologic disease
• Evoluting inflammatory process or neoplasia
• Treatment modifying coagulation
• Patients not affiliated to the French healthcare insurance

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
antro-pyloro-duodenal pressure	3h	the main outcome is the pressure measured using pressure sensors within the antrum, the pylorus, and the first part of the duodenum. This will be measured during 3h fast. Pressures measured in the antrum, the pylorus, and the duodenum wiil be compared between healthy volunteers and gastroparetic patients

Trial Locations

Locations (1)

Service de Physiologie; 🇫🇷 Rouen, Haute normandie, France