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Cortical Activity and Gait Function for Robotic Gait Training in Hemiparetic Stroke

Not Applicable
Completed
Conditions
Stroke
Interventions
Device: Robot-assisted gait training
Device: Treadmill gait training
Registration Number
NCT04054739
Lead Sponsor
National Rehabilitation Center, Seoul, Korea
Brief Summary

Effects of robot-assisted gait training on cortical activity and gait function in hemiparetic stroke

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
30
Inclusion Criteria
  • Hemiplegic patients secondary to first cerebrovascular accidents
  • Functional ambulation category score 3
  • 3 months ≤ Onset ≤ 12 months
  • Korean Mini-Mental State Examination score > 24
Exclusion Criteria
  • History of surgery of affected lower limb
  • Fracture of affected lower limb

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Robot-assisted gait trainingRobot-assisted gait trainingexperimental group that applied the end-effector robot-assisted gait training
Treadmill gait trainingTreadmill gait trainingcontrol group that applied the treadmill gait training
Primary Outcome Measures
NameTimeMethod
Range of motion of ankle, knee, and hip joint4 weeks from baseline

ankle, knee, and hip joint motion of sagittal plane during gait

oxygenated hemoglobin levels4 weeks from baseline

cortical activity of primary sensorimotor cortex, premotor cortex, supplementary motor areas, pre-supplementary motor areas, prefrontal cortex during gait

Secondary Outcome Measures
NameTimeMethod
Plantar pressurebaseline, 2 weeks after baseline, 4 weeks after baseline, 8 weeks after baseline

Plantar pressure (great toe, little toe, medial meta, lateral meta, medial arch, lateral arch, heel) during gait

Functional ambulation categorybaseline, 2 weeks after baseline, 4 weeks after baseline, 8 weeks after baseline

Functional Ambulation Category is used to assess gait ability with 6 levels ranging from 0 to 5 on the basis of the amount of physical support required, regardless of use of an assistive device

Timed up and go testbaseline, 2 weeks after baseline, 4 weeks after baseline, 8 weeks after baseline

a simple test used to assess a person's mobility and requires both static and dynamic balance

Balance test using force platebaseline, 2 weeks after baseline, 4 weeks after baseline, 8 weeks after baseline

Static standing balance as measured using a force plate: Changes in center-of-pressure velocity and area

Fugl-Meyer Assessmentbaseline, 2 weeks after baseline, 4 weeks after baseline, 8 weeks after baseline

Fugl-Meyer Assessment uses to examine the motor function and coordination of affected lower extremity. It includes 17 items of a 3-point ordinal scale, ranging 0-34, with higher scores indicating lower impairment.

Stroke impact scalebaseline, 2 weeks after baseline, 4 weeks after baseline, 8 weeks after baseline

health-related quality of life poststroke across 8 domains using a 5-point Likert scale, with the score ranging from 0 to 100 and a higher score indicating better health status

dual task - COWATbaseline, 2 weeks after baseline, 4 weeks after baseline, 8 weeks after baseline

Controlled Oral Word Association Test, abbreviated COWA or COWAT, is a verbal fluency test that measures spontaneous production of words belonging to the same category or beginning with some designated letter.

Electromyography of lower extremitiesbaseline, 2 weeks after baseline, 4 weeks after baseline, 8 weeks after baseline

Muscle activity of tibialis anterior, medial gastrocnemius, vastus medialis, biceps femoris, gluteus medius during gait.

modified Barthel indexbaseline, 2 weeks after baseline, 4 weeks after baseline, 8 weeks after baseline

Measure of physical disability used widely to assess behaviour relating to activities of daily living for stroke patients

Spatiotemporal gait parameter databaseline, 2 weeks after baseline, 4 weeks after baseline, 8 weeks after baseline

step length, step time, swing time, double limb support time during gait

total hemoglobin levelsbaseline, 2 weeks after baseline, 4 weeks after baseline, 8 weeks after baseline

cortical activity of primary sensorimotor cortex, premotor cortex, supplementary motor areas, pre-supplementary motor areas, prefrontal cortex during gait

Range of motion of ankle, knee, and hip jointbaseline, 2 weeks after baseline, 4 weeks after baseline, 8 weeks after baseline

ankle, knee, and hip joint motion of sagittal plane during gait

dual task - digit span testbaseline, 2 weeks after baseline, 4 weeks after baseline, 8 weeks after baseline

The digit span test is a way of measuring the storage capacity of a person's working memory.

deoxygenated hemoglobin levelsbaseline, 2 weeks after baseline, 4 weeks after baseline, 8 weeks after baseline

cortical activity of primary sensorimotor cortex, premotor cortex, supplementary motor areas, pre-supplementary motor areas, prefrontal cortex during gait

oxygenated hemoglobin levelsbaseline, 2 weeks after baseline, 4 weeks after baseline, 8 weeks after baseline

cortical activity of primary sensorimotor cortex, premotor cortex, supplementary motor areas, pre-supplementary motor areas, prefrontal cortex during gait

Berg Balance Scalebaseline, 2 weeks after baseline, 4 weeks after baseline, 8 weeks after baseline

Berg Balance Scale assess the functional balance ability of participants with observation of 14 tasks, representing functional movements common in daily life. Each task is scored on a five-point scale (0-4) following the guidelines of the test developers, and the maximum score on this test is 56 which indicates balance ability within the normal range.

10m walk testbaseline, 2 weeks after baseline, 4 weeks after baseline, 8 weeks after baseline

10m walk test is used to examine gait speed, in which participant was asked to walk on a 14 meter of walkway wearing harness with two conditions; with the fastest speed or with self-selected comfortable speed.

Falls efficacy scalebaseline, 2 weeks after baseline, 4 weeks after baseline, 8 weeks after baseline

Korean version of Falls efficacy scale asks subjects to rank their confidence about their ability not to fall while performing a variety of activities of daily living with a maximum score of 100

Beck depression inventorybaseline, 2 weeks after baseline, 4 weeks after baseline, 8 weeks after baseline

21-question multiple-choice self-report inventory, one of the most widely used psychometric tests

Dynamic gait indexbaseline, 2 weeks after baseline, 4 weeks after baseline, 8 weeks after baseline

a clinical tool to assess gait, balance and fall risk

Trial Locations

Locations (1)

National Rehabilitation Center

🇰🇷

Seoul, Korea, Republic of

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