The Dexametasone-CRH-test as a potential predictor of treatment effect in depression: a pilot study. - KIDSS

Psykiatri Nordväst, Karolinska Universitetssjukhuset Solna0 个研究点目标入组 40 人开始时间: 2011年7月19日最近更新: 2013年10月7日

适应症

试验速览

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•In total 40 subjects, aged 20-65 years, with depressive symptoms (MADRS =12) considered by their physician to need antidepressant treatment, will be recruited from primary care clinics in the Stockholm area. All subjects must be employed.
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range
•F.1.3 Elderly (>=65 years) no
•F.1.3.1 Number of subjects for this age range

•Alcohol or drug dependence, bipolar disorder, psychotic symptoms, acute suicide risk or current treatment with antidepressant drugs or psychotherapy, breastfeeding or pregnant, concomitant administration of pharmaceutical preparations containing substances which inhibit ACTH and/or cortisol, such as corticosteroids (except for dexamethasone 1.5 mg at the evening before the DEX-CRH test), antihistamines and antiserotoninergic substances and oxytocin,
•subjects with concomitant administration of vasopressin or its analogues will be excluded, since these substances lead to an increase of the potency of CRH Ferring,

发起方

Psykiatri Nordväst, Karolinska Universitetssjukhuset Solna