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Taper-shaped Cuff Endotracheal Tube Against Respiratory Infections

Not Applicable
Completed
Conditions
Postoperative Pneumonia
Interventions
Device: Endotracheal tube TaperGuard
Device: Endotracheal tube Hi-Contour Brandt
Registration Number
NCT01457248
Lead Sponsor
Groupe Hospitalier Pitie-Salpetriere
Brief Summary

The incidence of postoperative pneumonia after aortic surgery reaches 60%. In experimental lung model, endotracheal tube with taper-shaped cuff has been shown to decrease microaspiration. This effect has never been demonstrated in patients. The investigators hypothesize that use of endotracheal tube with taper-shaped cuff decreases the incidence of postoperative pneumonia in patients after aortic surgery.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
162
Inclusion Criteria
  • Age ≥ 18 ans
  • Elective aortic surgery
  • Admission in ICU after aortic surgery
Exclusion Criteria
  • Tracheostomized patients

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
endotracheal tube with taper-shaped cuffEndotracheal tube TaperGuard-
Endotracheal tube with cylindrical-shaped cuffEndotracheal tube Hi-Contour Brandt-
Primary Outcome Measures
NameTimeMethod
Incidence of first episode of postoperative pneumonia after aortic surgeryWithin the first 28 days after surgery
Secondary Outcome Measures
NameTimeMethod
MicroaspirationDay 1 and day 2
MortalityDay 28 and day 90
Length of ICU stayParticipants will be followed for the duration of ICU stay, an expected average of 3 weeks

Trial Locations

Locations (1)

Réanimation polyvalente, Département d'Anesthésie-Réanimation, Groupe Hospitalier Pitié-Salpêtrière

🇫🇷

Paris, France

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